Modeling neuron-astrocyte interactions: towards understanding synaptic plasticity and learning in the brain

    Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

    Abstract

    Spiking neural networks represent a third generation of artificial neural networks and are inspired by computational principles of neurons and synapses in the brain. In addition to neuronal mechanisms, astrocytic signaling can influence information transmission, plasticity and learning in the brain. In this study, we developed a new computational model to better understand the dynamics of mechanisms that lead to changes in information processing between a postsynaptic neuron and an astrocyte. We used a classical stimulation protocol of long-term plasticity to test the model functionality. The long-term goal of our work is to develop extended synapse models including neuron-astrocyte interactions to address plasticity and learning in cortical synapses. Our modeling studies will advance the development of novel learning algorithms to be used in the extended synapse models and spiking neural networks. The novel algorithms can provide a basis for artificial intelligence systems that can emulate the functionality of mammalian brain.
    Original languageEnglish
    Title of host publicationIntelligent Computing Theories and Application
    Subtitle of host publication13th International Conference, ICIC 2017, Liverpool, UK, August 7-10, 2017, Proceedings, Part II
    PublisherSpringer
    Pages157-168
    ISBN (Electronic)978-3-319-63312-1
    ISBN (Print)978-3-319-63311-4
    DOIs
    Publication statusPublished - 2017
    Publication typeA4 Article in conference proceedings
    EventInternational Conference on Intelligent Computing Theories and Application -
    Duration: 1 Jan 2000 → …

    Publication series

    Name Lecture Notes in Computer Science
    Volume10362
    ISSN (Electronic)1611-3349

    Conference

    ConferenceInternational Conference on Intelligent Computing Theories and Application
    Period1/01/00 → …

    Publication forum classification

    • Publication forum level 1

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