MRI Texture Analysis and Diffusion Tensor Imaging in Chronic Right Hemisphere Ischemic Stroke

Minna Sikiö, Paula Kölhi, Pertti Ryymin, Hannu J. Eskola, Prasun Dastidar

    Research output: Contribution to journalArticleScientificpeer-review

    15 Citations (Scopus)

    Abstract

    BACKGROUND AND PURPOSE: Diffusion tensor imaging (DTI) is shown to reveal changes caused by cerebral infarction. The aim of this study is to reveal those changes also in the conventional magnetic resonance (MR) images using a quantitative image analysis method, texture analysis (TA). METHODS: Thirty patients who had suffered their first ever infarction located on the right hemisphere underwent DTI and conventional MRI studies in the chronic phase. DTI parameters fractional anisotropy and mean diffusivity, as well as four second-order texture parameters were calculated. Interhemispheric differences and correlations between DTI and TA parameters were evaluated. RESULTS: Our DTI findings supported earlier studies as fractional anisotropy values were lowered and mean diffusivity values elevated in the lesion site, and ipsilateral cerebral peduncle, thalamus, and centrum semiovale compared to the unaffected side. Textural homogeneity parameters showed lower and complexity parameters higher values in the lesion site and ipsilateral centrum semiovale compared to the contralateral hemisphere. Correlation between the two methods was found in ipsilateral mesencephalon. CONCLUSIONS: In addition to DTI method, TA could assist in revealing the changes caused by infarction, also outside the lesion site. Damaged areas were found more heterogeneous and random in texture compared to unaffected sites.

    Original languageEnglish
    Pages (from-to)614-619
    Number of pages6
    JournalJournal of Neuroimaging
    Volume25
    Issue number4
    DOIs
    Publication statusPublished - 2015
    Publication typeA1 Journal article-refereed

    Keywords

    • Chronic infarction
    • Diffusion tensor imaging
    • Magnetic resonance imaging
    • Texture analysis

    Publication forum classification

    • Publication forum level 1

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