Multimorbidity among incident Finnish systemic lupus erythematosus patients during 2000–2017

Simo Kariniemi, Vappu Rantalaiho, Lauri J. Virta, Kari Puolakka, Tuulikki Sokka-Isler, Pia Elfving

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    9 Citations (Scopus)
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    Abstract

    The objective of the study was to examine the risk of other morbidities among patients with systemic lupus erythematosus (SLE). A total of 1006 adult new-onset SLE patients were identified during 1.1.2000- 31.12.2014 from the register of Social Insurance Institution. For each case three general population controls matched according to age, sex and place of residence at the index day were sampled from the population register. Both groups were followed up from the index date until the end of 2017 or until death. The national register on specialized care was explored to gather broadly their 12 organ-specific morbidities, which were found among 91.2% of SLE patients and 66.7% of comparators. The rate ratio (RR) was elevated in almost all disease groups. Musculoskeletal, cardiovascular and genitourinary conditions were the most common comorbidities with RRs of 1.82 (1.68 to 1.97), 1.91 (1.76 to 2.08) and 1.91 (1.73 to 2.09), respectively. Men with SLE had a significantly higher risk for diseases of the genitourinary system and endocrine, nutritional and metabolic diseases compared to women with SLE. The risk of concurrent morbidities is essential to note in the care of SLE patients.

    Original languageEnglish
    Pages (from-to)165-171
    JournalLUPUS
    Volume30
    Issue number1
    Early online date22 Oct 2020
    DOIs
    Publication statusPublished - 2021
    Publication typeA1 Journal article-refereed

    Keywords

    • cardiovascular disease
    • comorbidity
    • gender
    • morbidity
    • Systemic lupus erythematosus

    Publication forum classification

    • Publication forum level 1

    ASJC Scopus subject areas

    • Rheumatology

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