N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization

Jun-Jie Koh; Chandra Verma; Ai Ling Tan; Roger W Beuerman; Shouping Liu; Huifen Lin; Caroline Vonny; Yu Siang Chew; Li Mei Pang; Thet Tun Aung; Li Jianguo; Rajamani Lakshminarayanan; Donald T H Tan

doi:10.1021/acs.jmedchem.5b00628

N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization

Jun-Jie Koh, Chandra Verma, Ai Ling Tan, Roger W Beuerman, Shouping Liu, Huifen Lin, Caroline Vonny, Yu Siang Chew, Li Mei Pang, Thet Tun Aung, Li Jianguo, Rajamani Lakshminarayanan, Donald T H Tan

Research output: Contribution to journal › Article › Scientific › peer-review

32 Citations (Scopus)

Original language	English
Pages (from-to)	6533-6548
Journal	JOURNAL OF MEDICINAL CHEMISTRY
Volume	58
Issue number	16
DOIs	https://doi.org/10.1021/acs.jmedchem.5b00628
Publication status	Published - 2015
Publication type	A1 Journal article-refereed

Publication forum classification

Publication forum level 3

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10.1021/acs.jmedchem.5b00628

Cite this

Koh, J-J., Verma, C., Tan, A. L., Beuerman, R. W., Liu, S., Lin, H., Vonny, C., Chew, Y. S., Pang, L. M., Aung, T. T., Jianguo, L., Lakshminarayanan, R., & Tan, D. T. H. (2015). N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. JOURNAL OF MEDICINAL CHEMISTRY, 58(16), 6533-6548. https://doi.org/10.1021/acs.jmedchem.5b00628

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title = "N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization",

author = "Jun-Jie Koh and Chandra Verma and Tan, {Ai Ling} and Beuerman, {Roger W} and Shouping Liu and Huifen Lin and Caroline Vonny and Chew, {Yu Siang} and Pang, {Li Mei} and Aung, {Thet Tun} and Li Jianguo and Rajamani Lakshminarayanan and Tan, {Donald T H}",

year = "2015",

doi = "10.1021/acs.jmedchem.5b00628",

language = "English",

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Koh, J-J, Verma, C, Tan, AL, Beuerman, RW, Liu, S, Lin, H, Vonny, C, Chew, YS, Pang, LM, Aung, TT, Jianguo, L, Lakshminarayanan, R & Tan, DTH 2015, 'N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization', JOURNAL OF MEDICINAL CHEMISTRY, vol. 58, no. 16, pp. 6533-6548. https://doi.org/10.1021/acs.jmedchem.5b00628

TY - JOUR

T1 - N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization

AU - Koh, Jun-Jie

AU - Verma, Chandra

AU - Tan, Ai Ling

AU - Beuerman, Roger W

AU - Liu, Shouping

AU - Lin, Huifen

AU - Vonny, Caroline

AU - Chew, Yu Siang

AU - Pang, Li Mei

AU - Aung, Thet Tun

AU - Jianguo, Li

AU - Lakshminarayanan, Rajamani

AU - Tan, Donald T H

PY - 2015

Y1 - 2015

U2 - 10.1021/acs.jmedchem.5b00628

DO - 10.1021/acs.jmedchem.5b00628

M3 - Article

SN - 0022-2623

VL - 58

SP - 6533

EP - 6548

JO - JOURNAL OF MEDICINAL CHEMISTRY

JF - JOURNAL OF MEDICINAL CHEMISTRY

IS - 16

ER -