Nanosuspensions of poorly soluble drugs: Preparation and development by wet milling

Peng Liu; Xinyu Rong; Johanna Laru; Bert van Veen; Juha Kiesvaara; Jouni Hirvonen; Timo Laaksonen; Leena Peltonen

doi:10.1016/j.ijpharm.2011.03.050

Nanosuspensions of poorly soluble drugs: Preparation and development by wet milling

Peng Liu, Xinyu Rong, Johanna Laru, Bert van Veen, Juha Kiesvaara, Jouni Hirvonen, Timo Laaksonen, Leena Peltonen

Research output: Contribution to journal › Article › Scientific › peer-review

165 Citations (Scopus)

Original language	English
Pages (from-to)	215-222
Number of pages	8
Journal	International Journal of Pharmaceutics
Volume	411
Issue number	1-2
DOIs	https://doi.org/10.1016/j.ijpharm.2011.03.050
Publication status	Published - 2011
Publication type	A1 Journal article-refereed

Keywords

Hydrophobic drug
Nanosuspensions
Wet milling
Stabilizer
Dissolution rate
PARTICLE-SIZE REDUCTION
DISSOLUTION RATE
NANOCRYSTALS
FORMULATION
STABILIZATION
TECHNOLOGY
DELIVERY
NANOPARTICLES
INDOMETHACIN
SOLUBILITY
317 Pharmacy

Access to Document

10.1016/j.ijpharm.2011.03.050

Cite this

@article{04301d48a55547ccac05e054926eb2d9,

title = "Nanosuspensions of poorly soluble drugs: Preparation and development by wet milling",

keywords = "Hydrophobic drug, Nanosuspensions, Wet milling, Stabilizer, Dissolution rate, PARTICLE-SIZE REDUCTION, DISSOLUTION RATE, NANOCRYSTALS, FORMULATION, STABILIZATION, TECHNOLOGY, DELIVERY, NANOPARTICLES, INDOMETHACIN, SOLUBILITY, 317 Pharmacy",

author = "Peng Liu and Xinyu Rong and Johanna Laru and {van Veen}, Bert and Juha Kiesvaara and Jouni Hirvonen and Timo Laaksonen and Leena Peltonen",

year = "2011",

doi = "10.1016/j.ijpharm.2011.03.050",

language = "English",

volume = "411",

pages = "215--222",

journal = "International Journal of Pharmaceutics",

issn = "0378-5173",

publisher = "Elsevier",

number = "1-2",

}

Nanosuspensions of poorly soluble drugs: Preparation and development by wet milling. / Liu, Peng; Rong, Xinyu; Laru, Johanna; van Veen, Bert; Kiesvaara, Juha; Hirvonen, Jouni; Laaksonen, Timo; Peltonen, Leena.

In: International Journal of Pharmaceutics, Vol. 411, No. 1-2, 2011, p. 215-222.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Nanosuspensions of poorly soluble drugs: Preparation and development by wet milling

AU - Liu, Peng

AU - Rong, Xinyu

AU - Laru, Johanna

AU - van Veen, Bert

AU - Kiesvaara, Juha

AU - Hirvonen, Jouni

AU - Laaksonen, Timo

AU - Peltonen, Leena

PY - 2011

Y1 - 2011

KW - Hydrophobic drug

KW - Nanosuspensions

KW - Wet milling

KW - Stabilizer

KW - Dissolution rate

KW - PARTICLE-SIZE REDUCTION

KW - DISSOLUTION RATE

KW - NANOCRYSTALS

KW - FORMULATION

KW - STABILIZATION

KW - TECHNOLOGY

KW - DELIVERY

KW - NANOPARTICLES

KW - INDOMETHACIN

KW - SOLUBILITY

KW - 317 Pharmacy

U2 - 10.1016/j.ijpharm.2011.03.050

DO - 10.1016/j.ijpharm.2011.03.050

M3 - Article

VL - 411

SP - 215

EP - 222

JO - International Journal of Pharmaceutics

JF - International Journal of Pharmaceutics

SN - 0378-5173

IS - 1-2

ER -