Nanosuspensions of poorly soluble drugs: Preparation and development by wet milling

Peng Liu, Xinyu Rong, Johanna Laru, Bert van Veen, Juha Kiesvaara, Jouni Hirvonen, Timo Laaksonen, Leena Peltonen

    Research output: Contribution to journalArticleScientificpeer-review

    165 Citations (Scopus)
    Original languageEnglish
    Pages (from-to)215-222
    Number of pages8
    JournalInternational Journal of Pharmaceutics
    Volume411
    Issue number1-2
    DOIs
    Publication statusPublished - 2011
    Publication typeA1 Journal article-refereed

    Keywords

    • Hydrophobic drug
    • Nanosuspensions
    • Wet milling
    • Stabilizer
    • Dissolution rate
    • PARTICLE-SIZE REDUCTION
    • DISSOLUTION RATE
    • NANOCRYSTALS
    • FORMULATION
    • STABILIZATION
    • TECHNOLOGY
    • DELIVERY
    • NANOPARTICLES
    • INDOMETHACIN
    • SOLUBILITY
    • 317 Pharmacy

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