Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes

A. Aspatwar; H.M. Becker; N.K. Parvathaneni; M. Hammaren; A. Svorjova; H. Barker; C.T. Supuran; L. Dubois; P. Lambin; M. Parikka; S. Parkkila; J.-Y. Winum

doi:10.1080/14756366.2018.1482285

Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes

A. Aspatwar, H.M. Becker, N.K. Parvathaneni, M. Hammaren, A. Svorjova, H. Barker, C.T. Supuran, L. Dubois, P. Lambin, M. Parikka, S. Parkkila, J.-Y. Winum

Research output: Contribution to journal › Article › Scientific › peer-review

11 Citations (Scopus)

Original language	English
Pages (from-to)	1064-1073
Journal	JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Volume	33
Issue number	1
DOIs	https://doi.org/10.1080/14756366.2018.1482285
Publication status	Published - 2018
Publication type	A1 Journal article-refereed

Keywords

Nitroimidazoles
Xenopus oocytes
carbonic anhydrase IX
in vivo inhibition
zebrafish

Publication forum classification

Publication forum level 1

Access to Document

10.1080/14756366.2018.1482285

http://urn.fi/urn:nbn:fi:uta-201807112311

Cite this

Aspatwar, A., Becker, H. M., Parvathaneni, N. K., Hammaren, M., Svorjova, A., Barker, H., Supuran, C. T., Dubois, L., Lambin, P., Parikka, M., Parkkila, S., & Winum, J-Y. (2018). Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 33(1), 1064-1073. https://doi.org/10.1080/14756366.2018.1482285

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title = "Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes",

keywords = "Nitroimidazoles, Xenopus oocytes, carbonic anhydrase IX, in vivo inhibition, zebrafish, Nitroimidazoles, Xenopus oocytes, carbonic anhydrase IX, in vivo inhibition, zebrafish",

author = "A. Aspatwar and H.M. Becker and N.K. Parvathaneni and M. Hammaren and A. Svorjova and H. Barker and C.T. Supuran and L. Dubois and P. Lambin and M. Parikka and S. Parkkila and J.-Y. Winum",

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Aspatwar, A, Becker, HM, Parvathaneni, NK, Hammaren, M, Svorjova, A, Barker, H, Supuran, CT, Dubois, L, Lambin, P, Parikka, M , Parkkila, S & Winum, J-Y 2018, 'Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes', JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 33, no. 1, pp. 1064-1073. https://doi.org/10.1080/14756366.2018.1482285

Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes. / Aspatwar, A.; Becker, H.M.; Parvathaneni, N.K. et al.

In: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, Vol. 33, No. 1, 2018, p. 1064-1073.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes

AU - Aspatwar, A.

AU - Becker, H.M.

AU - Parvathaneni, N.K.

AU - Hammaren, M.

AU - Svorjova, A.

AU - Barker, H.

AU - Supuran, C.T.

AU - Dubois, L.

AU - Lambin, P.

AU - Parikka, M.

AU - Parkkila, S.

AU - Winum, J.-Y.

PY - 2018

Y1 - 2018

KW - Nitroimidazoles

KW - Xenopus oocytes

KW - carbonic anhydrase IX

KW - in vivo inhibition

KW - zebrafish

KW - Nitroimidazoles

KW - Xenopus oocytes

KW - carbonic anhydrase IX

KW - in vivo inhibition

KW - zebrafish

U2 - 10.1080/14756366.2018.1482285

DO - 10.1080/14756366.2018.1482285

M3 - Article

SN - 1475-6366

VL - 33

SP - 1064

EP - 1073

JO - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

JF - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IS - 1

ER -