Organizational structure of the transcriptional regulatory network of yeast: Periodic genes

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1 Citation (Scopus)

Abstract

In this paper we investigate the organizational structure of the transcriptional regulatory network of S. cerevisiae with respect to the connectivity structure of periodic genes. We demonstrate that the giant strongly connected component plays a prominent role serving as central connector for genes experimentally found to be periodically expressed during the cell cycle of yeast. Numerically, we find by randomization of the gene labels that this organizational structure is unlikely to be formed by chance.

Original languageEnglish
Title of host publicationLecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering
Pages140-148
Number of pages9
Volume4 LNICST
EditionPART 1
DOIs
Publication statusPublished - 2009
Externally publishedYes
Publication typeA4 Article in conference proceedings
Event1st International Conference on Complex Sciences: Theory and Applications, Complex 2009 - Shanghai, China
Duration: 23 Feb 200925 Feb 2009

Publication series

NameLecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering
NumberPART 1
Volume4 LNICST
ISSN (Print)18678211

Conference

Conference1st International Conference on Complex Sciences: Theory and Applications, Complex 2009
Country/TerritoryChina
CityShanghai
Period23/02/0925/02/09

Keywords

  • Causality
  • Graph theory
  • Periodic genes
  • Randomization
  • Transcriptional regulatory network

ASJC Scopus subject areas

  • Computer Networks and Communications

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