Persistence of Hepatitis B Immune Memory Until 6 Years of Age Following Hexavalent DTaP-IPV-HB-PRP~T Vaccination in a 3-, 5- and 11- to 12-month Schedule and Response to a Subsequent Hepatitis B Challenge Vaccination

Miia Virta; Anu Soininen; Dhaval M Patel; Céline Petit; Cynthia Tabar; Olga Lyabis

doi:10.1097/INF.0000000000002954

Persistence of Hepatitis B Immune Memory Until 6 Years of Age Following Hexavalent DTaP-IPV-HB-PRP~T Vaccination in a 3-, 5- and 11- to 12-month Schedule and Response to a Subsequent Hepatitis B Challenge Vaccination

Miia Virta
, Anu Soininen
, Dhaval M Patel
, Céline Petit
, Cynthia Tabar
, Olga Lyabis

Research output: Contribution to journal › Article › Scientific › peer-review

4 Citations (Scopus)

Abstract

Anti-hepatitis B (HBs) antibody persistence and hepatitis B challenge were evaluated at 6 years of age following vaccination of fully liquid DTaP-IPV-HB-PRP~T or reconstituted DTaP-IPV-HB//PRP~T at 3, 5, 11-12 months of age. At 6 years, 53.8% and 73.5% had seroprotective anti-HBs antibodies (≥10 mIU/mL), increasing to 96.7% and 95.9% postchallenge, confirming a strong anamnestic response in primed vaccinees.

Original language	English
Pages (from-to)	e28-e30
Journal	The Pediatric infectious disease journal
Volume	40
Issue number	1
DOIs	https://doi.org/10.1097/INF.0000000000002954
Publication status	Published - Jan 2021
Publication type	A1 Journal article-refereed

Keywords

Child
Diphtheria-Tetanus-Pertussis Vaccine/administration & dosage
Female
Haemophilus Vaccines/administration & dosage
Hepatitis B Antibodies/blood
Hepatitis B Vaccines/administration & dosage
Humans
Immunization Schedule
Immunologic Memory/immunology
Male
Poliovirus Vaccine, Inactivated/administration & dosage
Vaccines, Combined/administration & dosage

Publication forum classification

Publication forum level 1

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Virta, M., Soininen, A., Patel, D. M., Petit, C., Tabar, C., & Lyabis, O. (2021). Persistence of Hepatitis B Immune Memory Until 6 Years of Age Following Hexavalent DTaP-IPV-HB-PRP~T Vaccination in a 3-, 5- and 11- to 12-month Schedule and Response to a Subsequent Hepatitis B Challenge Vaccination. The Pediatric infectious disease journal, 40(1), e28-e30. https://doi.org/10.1097/INF.0000000000002954

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title = "Persistence of Hepatitis B Immune Memory Until 6 Years of Age Following Hexavalent DTaP-IPV-HB-PRP\textasciitilde{}T Vaccination in a 3-, 5- and 11- to 12-month Schedule and Response to a Subsequent Hepatitis B Challenge Vaccination",

abstract = "Anti-hepatitis B (HBs) antibody persistence and hepatitis B challenge were evaluated at 6 years of age following vaccination of fully liquid DTaP-IPV-HB-PRP\textasciitilde{}T or reconstituted DTaP-IPV-HB//PRP\textasciitilde{}T at 3, 5, 11-12 months of age. At 6 years, 53.8\% and 73.5\% had seroprotective anti-HBs antibodies (≥10 mIU/mL), increasing to 96.7\% and 95.9\% postchallenge, confirming a strong anamnestic response in primed vaccinees.",

keywords = "Child, Diphtheria-Tetanus-Pertussis Vaccine/administration \& dosage, Female, Haemophilus Vaccines/administration \& dosage, Hepatitis B Antibodies/blood, Hepatitis B Vaccines/administration \& dosage, Humans, Immunization Schedule, Immunologic Memory/immunology, Male, Poliovirus Vaccine, Inactivated/administration \& dosage, Vaccines, Combined/administration \& dosage",

author = "Miia Virta and Anu Soininen and Patel, \{Dhaval M\} and C{\'e}line Petit and Cynthia Tabar and Olga Lyabis",

year = "2021",

month = jan,

doi = "10.1097/INF.0000000000002954",

language = "English",

volume = "40",

pages = "e28--e30",

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Virta, M, Soininen, A, Patel, DM, Petit, C, Tabar, C & Lyabis, O 2021, 'Persistence of Hepatitis B Immune Memory Until 6 Years of Age Following Hexavalent DTaP-IPV-HB-PRP~T Vaccination in a 3-, 5- and 11- to 12-month Schedule and Response to a Subsequent Hepatitis B Challenge Vaccination', The Pediatric infectious disease journal, vol. 40, no. 1, pp. e28-e30. https://doi.org/10.1097/INF.0000000000002954

Persistence of Hepatitis B Immune Memory Until 6 Years of Age Following Hexavalent DTaP-IPV-HB-PRP~T Vaccination in a 3-, 5- and 11- to 12-month Schedule and Response to a Subsequent Hepatitis B Challenge Vaccination. / Virta, Miia; Soininen, Anu; Patel, Dhaval M et al.
In: The Pediatric infectious disease journal, Vol. 40, No. 1, 01.2021, p. e28-e30.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Persistence of Hepatitis B Immune Memory Until 6 Years of Age Following Hexavalent DTaP-IPV-HB-PRP~T Vaccination in a 3-, 5- and 11- to 12-month Schedule and Response to a Subsequent Hepatitis B Challenge Vaccination

AU - Virta, Miia

AU - Soininen, Anu

AU - Patel, Dhaval M

AU - Petit, Céline

AU - Tabar, Cynthia

AU - Lyabis, Olga

PY - 2021/1

Y1 - 2021/1

N2 - Anti-hepatitis B (HBs) antibody persistence and hepatitis B challenge were evaluated at 6 years of age following vaccination of fully liquid DTaP-IPV-HB-PRP~T or reconstituted DTaP-IPV-HB//PRP~T at 3, 5, 11-12 months of age. At 6 years, 53.8% and 73.5% had seroprotective anti-HBs antibodies (≥10 mIU/mL), increasing to 96.7% and 95.9% postchallenge, confirming a strong anamnestic response in primed vaccinees.

AB - Anti-hepatitis B (HBs) antibody persistence and hepatitis B challenge were evaluated at 6 years of age following vaccination of fully liquid DTaP-IPV-HB-PRP~T or reconstituted DTaP-IPV-HB//PRP~T at 3, 5, 11-12 months of age. At 6 years, 53.8% and 73.5% had seroprotective anti-HBs antibodies (≥10 mIU/mL), increasing to 96.7% and 95.9% postchallenge, confirming a strong anamnestic response in primed vaccinees.

KW - Child

KW - Diphtheria-Tetanus-Pertussis Vaccine/administration & dosage

KW - Female

KW - Haemophilus Vaccines/administration & dosage

KW - Hepatitis B Antibodies/blood

KW - Hepatitis B Vaccines/administration & dosage

KW - Humans

KW - Immunization Schedule

KW - Immunologic Memory/immunology

KW - Male

KW - Poliovirus Vaccine, Inactivated/administration & dosage

KW - Vaccines, Combined/administration & dosage

U2 - 10.1097/INF.0000000000002954

DO - 10.1097/INF.0000000000002954

M3 - Article

C2 - 33284254

SN - 1532-0987

VL - 40

SP - e28-e30

JO - The Pediatric infectious disease journal

JF - The Pediatric infectious disease journal

IS - 1

ER -

Virta M, Soininen A, Patel DM, Petit C, Tabar C, Lyabis O. Persistence of Hepatitis B Immune Memory Until 6 Years of Age Following Hexavalent DTaP-IPV-HB-PRP~T Vaccination in a 3-, 5- and 11- to 12-month Schedule and Response to a Subsequent Hepatitis B Challenge Vaccination. The Pediatric infectious disease journal. 2021 Jan;40(1):e28-e30. doi: 10.1097/INF.0000000000002954