Polycomb Repressive Complex 2 Enacts Wnt Signaling in Intestinal Homeostasis and Contributes to the Instigation of Stemness in Diseases Entailing Epithelial Hyperplasia or Neoplasia

Mikko Oittinen; Alina Popp; Kalle Kurppa; Katri Lindfors; Markku Mäki; Minna Kaikkonen; Keijo Viiri

doi:10.1002/stem.2479

Polycomb Repressive Complex 2 Enacts Wnt Signaling in Intestinal Homeostasis and Contributes to the Instigation of Stemness in Diseases Entailing Epithelial Hyperplasia or Neoplasia

Mikko Oittinen, Alina Popp, Kalle Kurppa, Katri Lindfors, Markku Mäki, Minna Kaikkonen, Keijo Viiri

Research output: Contribution to journal › Article › Scientific › peer-review

29 Citations (Scopus)

Original language	English
Pages (from-to)	445-457
Journal	Stem Cells
Volume	35
Issue number	2
Early online date	29 Aug 2016
DOIs	https://doi.org/10.1002/stem.2479
Publication status	Published - 2017
Publication type	A1 Journal article-refereed

Keywords

Wnt signaling
celiac disease
crypt hyperplasia
enterocyte
intestinal stem cells
polycomb repressive complex 2 (PRC2)

Publication forum classification

Publication forum level 2

Access to Document

10.1002/stem.2479

Adult Stem Cell Organoids Facility
Viiri, K. (Contact) & Leppiniemi, J. (Contact)
Facility/equipment: Facility

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@article{e965a0e70b464f1784c3320687c7f764,

title = "Polycomb Repressive Complex 2 Enacts Wnt Signaling in Intestinal Homeostasis and Contributes to the Instigation of Stemness in Diseases Entailing Epithelial Hyperplasia or Neoplasia",

keywords = "Wnt signaling, celiac disease, crypt hyperplasia, enterocyte, intestinal stem cells, polycomb repressive complex 2 (PRC2), Wnt signaling, celiac disease, crypt hyperplasia, enterocyte, intestinal stem cells, polycomb repressive complex 2 (PRC2)",

author = "Mikko Oittinen and Alina Popp and Kalle Kurppa and Katri Lindfors and Markku M{\"a}ki and Minna Kaikkonen and Keijo Viiri",

year = "2017",

doi = "10.1002/stem.2479",

language = "English",

volume = "35",

pages = "445--457",

journal = "Stem Cells",

issn = "1066-5099",

publisher = "Oxford University Press",

number = "2",

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TY - JOUR

T1 - Polycomb Repressive Complex 2 Enacts Wnt Signaling in Intestinal Homeostasis and Contributes to the Instigation of Stemness in Diseases Entailing Epithelial Hyperplasia or Neoplasia

AU - Oittinen, Mikko

AU - Popp, Alina

AU - Kurppa, Kalle

AU - Lindfors, Katri

AU - Mäki, Markku

AU - Kaikkonen, Minna

AU - Viiri, Keijo

PY - 2017

Y1 - 2017

KW - Wnt signaling

KW - celiac disease

KW - crypt hyperplasia

KW - enterocyte

KW - intestinal stem cells

KW - polycomb repressive complex 2 (PRC2)

KW - Wnt signaling

KW - celiac disease

KW - crypt hyperplasia

KW - enterocyte

KW - intestinal stem cells

KW - polycomb repressive complex 2 (PRC2)

U2 - 10.1002/stem.2479

DO - 10.1002/stem.2479

M3 - Article

SN - 1066-5099

VL - 35

SP - 445

EP - 457

JO - Stem Cells

JF - Stem Cells

IS - 2

ER -

Polycomb Repressive Complex 2 Enacts Wnt Signaling in Intestinal Homeostasis and Contributes to the Instigation of Stemness in Diseases Entailing Epithelial Hyperplasia or Neoplasia

Keywords

Publication forum classification

Access to Document

Equipment

Adult Stem Cell Organoids Facility

Cite this