Pyrazine-Fused Triterpenoids Block the TRPA1 Ion Channel in Vitro and Inhibit TRPA1-Mediated Acute Inflammation in Vivo

I. Mäki-Opas, M. Hämäläinen, L.J. Moilanen, R. Haavikko, T.J. Ahonen, S. Alakurtti, V.M. Moreira, K. Muraki, J. Yli-Kauhaluoma, E. Moilanen

Research output: Contribution to journalArticleScientificpeer-review

3 Citations (Scopus)
Original languageEnglish
Pages (from-to)2848-2857
JournalACS Chemical Neuroscience
Issue number6
Publication statusPublished - 2019
Publication typeA1 Journal article-refereed


  • TRPA1
  • Transient receptor potential channels
  • inflammation
  • natural compounds
  • pain
  • triterpenoids

Publication forum classification

  • Publication forum level 1

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