Quality of life of recently treated patients with breast cancer

Heidi Penttinen, Mervi Rautalin, Risto Roine, Tiina Jahkola, Pirkko Liisa Kellokumpu-Lehtinen, Riikka Huovinen, Hannu Kautiainen, Salme Järvenpää, Liisa Hakamies-Blomqvist, Carl Blomqvist, Tiina Saarto

Research output: Contribution to journalArticleScientificpeer-review

6 Citations (Scopus)


Aim: To investigate whether the negative quality of life result of a large randomized exercise intervention study (BREX) was due to considerable spontaneous recovery after adjuvant treatments. Patients and Methods: The change in QoL was studied in the control patients of the BREX study (Group 1) and a group of similar follow-up patients that did not participate in any intervention study (Group 2). QoL was measured by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 with the breast cancer module supplement 6 and 12 months after surgery. Results: QoL improved in both groups between 6 and 12 months after surgery. The improvement was similar in both groups for global QoL and for most of the QoL sub-scales. Conclusion: No evidence was found to support the hypothesis that participation in an exercise intervention per se significantly improves QoL. Spontaneous improvement in QoL began during the first six months after the primary treatments, which might have confounded the results of the intervention of the BREX study.

Original languageEnglish
Pages (from-to)1201-1206
Number of pages6
JournalAnticancer Research
Issue number3
Publication statusPublished - 2014
Publication typeA1 Journal article-refereed


  • Breast cancer
  • Quality of life
  • Rehabilitation

Publication forum classification

  • Publication forum level 1


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