Quantitative urine proteomics in pregnant women for the identification of predictive biomarkers for preeclampsia

Sakari Joenväärä; Matilda Holm; Mayank Saraswat; Rahul Agarwal; Tiialotta Tohmola; Eero Kajantie; Katri Räikkönen; Hannele Laivuori; Pia M. Villa; Esa Hämäläinen; Risto Renkonen

doi:10.1186/s41231-022-00108-6

Quantitative urine proteomics in pregnant women for the identification of predictive biomarkers for preeclampsia

Sakari Joenväärä, Matilda Holm, Mayank Saraswat, Rahul Agarwal, Tiialotta Tohmola, Eero Kajantie, Katri Räikkönen, Hannele Laivuori, Pia M. Villa, Esa Hämäläinen, Risto Renkonen

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Abstract

Preeclampsia (PE) is a life-threatening disease characterized by elevated blood pressure and proteinuria. Predictive biomarkers of PE are needed, especially those predicting PE in early pregnancy. The aim of this pilot study was to identify urine proteins that could be candidates for new non-invasive markers for PE.

Original language	English
Article number	1
Number of pages	12
Journal	Translational Medicine Communications
Volume	7
Issue number	1
DOIs	https://doi.org/10.1186/s41231-022-00108-6
Publication status	Published - 2022
Publication type	A1 Journal article-refereed

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https://urn.fi/URN:NBN:fi:tuni-202302162440Licence: CC BY

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Joenväärä, S., Holm, M., Saraswat, M., Agarwal, R., Tohmola, T., Kajantie, E., Räikkönen, K., Laivuori, H., Villa, P. M., Hämäläinen, E., & Renkonen, R. (2022). Quantitative urine proteomics in pregnant women for the identification of predictive biomarkers for preeclampsia. Translational Medicine Communications, 7(1), [1]. https://doi.org/10.1186/s41231-022-00108-6

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abstract = "Preeclampsia (PE) is a life-threatening disease characterized by elevated blood pressure and proteinuria. Predictive biomarkers of PE are needed, especially those predicting PE in early pregnancy. The aim of this pilot study was to identify urine proteins that could be candidates for new non-invasive markers for PE.",

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AU - Joenväärä, Sakari

AU - Holm, Matilda

AU - Saraswat, Mayank

AU - Agarwal, Rahul

AU - Tohmola, Tiialotta

AU - Kajantie, Eero

AU - Räikkönen, Katri

AU - Laivuori, Hannele

AU - Villa, Pia M.

AU - Hämäläinen, Esa

AU - Renkonen, Risto

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AB - Preeclampsia (PE) is a life-threatening disease characterized by elevated blood pressure and proteinuria. Predictive biomarkers of PE are needed, especially those predicting PE in early pregnancy. The aim of this pilot study was to identify urine proteins that could be candidates for new non-invasive markers for PE.

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Quantitative urine proteomics in pregnant women for the identification of predictive biomarkers for preeclampsia

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