(R)-(3-amino-2-fluropropyl)phosphinic acid (AZD3355) a novel GABA-B receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action

A Lehmann; M Antonsson; AA Holmberg; LA Blackshaw; L Brändén; H Bräuner-Osborne; B Christriansen; J Dent; T Elebring; B-M Jacobson; J Jensen; JP Mattsson; K Nilsson; SS Oja; AJ Page; P Saransaari; S von Unge

doi:10.1124/jpet.109.153593

(R)-(3-amino-2-fluropropyl)phosphinic acid (AZD3355) a novel GABA-B receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action

A Lehmann, M Antonsson, AA Holmberg, LA Blackshaw, L Brändén, H Bräuner-Osborne, B Christriansen, J Dent, T Elebring, B-M Jacobson, J Jensen, JP Mattsson, K Nilsson, SS Oja, AJ Page, P Saransaari, S von Unge

Research output: Contribution to journal › Article › Scientific › peer-review

52 Citations (Scopus)

Original language	English
Pages (from-to)	504-512
Journal	JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Volume	331
Issue number	2
DOIs	https://doi.org/10.1124/jpet.109.153593
Publication status	Published - 2009
Publication type	A1 Journal article-refereed

Keywords

amino acid

Access to Document

10.1124/jpet.109.153593

Cite this

Lehmann, A., Antonsson, M., Holmberg, AA., Blackshaw, LA., Brändén, L., Bräuner-Osborne, H., Christriansen, B., Dent, J., Elebring, T., Jacobson, B.-M., Jensen, J., Mattsson, JP., Nilsson, K., Oja, SS., Page, AJ., Saransaari, P., & von Unge, S. (2009). (R)-(3-amino-2-fluropropyl)phosphinic acid (AZD3355) a novel GABA-B receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 331(2), 504-512. https://doi.org/10.1124/jpet.109.153593

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title = "(R)-(3-amino-2-fluropropyl)phosphinic acid (AZD3355) a novel GABA-B receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action",

keywords = "amino acid, amino acid",

author = "A Lehmann and M Antonsson and AA Holmberg and LA Blackshaw and L Br{\"a}nd{\'e}n and H Br{\"a}uner-Osborne and B Christriansen and J Dent and T Elebring and B-M Jacobson and J Jensen and JP Mattsson and K Nilsson and SS Oja and AJ Page and P Saransaari and {von Unge}, S",

year = "2009",

doi = "10.1124/jpet.109.153593",

language = "English",

volume = "331",

pages = "504--512",

journal = "JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS",

issn = "0022-3565",

publisher = "American Society for Pharmacology and Experimental Therapeutics",

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Lehmann, A, Antonsson, M, Holmberg, AA, Blackshaw, LA, Brändén, L, Bräuner-Osborne, H, Christriansen, B, Dent, J, Elebring, T, Jacobson, B-M, Jensen, J, Mattsson, JP, Nilsson, K, Oja, SS, Page, AJ, Saransaari, P & von Unge, S 2009, '(R)-(3-amino-2-fluropropyl)phosphinic acid (AZD3355) a novel GABA-B receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action', JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 331, no. 2, pp. 504-512. https://doi.org/10.1124/jpet.109.153593

(R)-(3-amino-2-fluropropyl)phosphinic acid (AZD3355) a novel GABA-B receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action. / Lehmann, A; Antonsson, M; Holmberg, AA et al.
In: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Vol. 331, No. 2, 2009, p. 504-512.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - (R)-(3-amino-2-fluropropyl)phosphinic acid (AZD3355) a novel GABA-B receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action

AU - Lehmann, A

AU - Antonsson, M

AU - Holmberg, AA

AU - Blackshaw, LA

AU - Brändén, L

AU - Bräuner-Osborne, H

AU - Christriansen, B

AU - Dent, J

AU - Elebring, T

AU - Jacobson, B-M

AU - Jensen, J

AU - Mattsson, JP

AU - Nilsson, K

AU - Oja, SS

AU - Page, AJ

AU - Saransaari, P

AU - von Unge, S

PY - 2009

Y1 - 2009

KW - amino acid

U2 - 10.1124/jpet.109.153593

DO - 10.1124/jpet.109.153593

M3 - Article

SN - 0022-3565

VL - 331

SP - 504

EP - 512

JO - JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

JF - JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IS - 2

ER -

Lehmann A, Antonsson M, Holmberg AA, Blackshaw LA, Brändén L, Bräuner-Osborne H et al. (R)-(3-amino-2-fluropropyl)phosphinic acid (AZD3355) a novel GABA-B receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2009;331(2):504-512. doi: 10.1124/jpet.109.153593