Abstract
Preferential Rh(II) carbenoid intramolecular C-H versus O-H insertion derived from R-diazo-acetamides can be achieved in water by using an appropriate combination of the catalyst and amide groups, which creates a larger hydrophobic environment around the reactive carbenoid center.
Original language | English |
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Pages (from-to) | 5489-5497 |
Number of pages | 9 |
Journal | Journal of Organic Chemistry |
Volume | 71 |
Issue number | 15 |
DOIs | |
Publication status | Published - 21 Jul 2006 |
Externally published | Yes |
Publication type | A1 Journal article-refereed |
Keywords
- RHODIUM(II) CATALYZED-REACTIONS
- ORGANIC-REACTIONS
- ALPHA-DIAZOACETAMIDES
- N-ARYLDIAZOAMIDES
- YLIDE FORMATION
- DIRHODIUM(II)
- CARBENOIDS
- CYCLOPROPANATION
- SOLVENT
- ENANTIOSELECTIVITY