SARS-CoV-2 late shedding may be infectious between immunocompromised hosts

Research output: Contribution to journalArticleScientific


Background: Immunocompromised patients shed SARS-CoV-2 for extended periods, but to our knowledge person-to-person transmission from late shedding has not been reported. The case: We present a case in which a COVID-19 patient infected another over 28 days after the patient’s initial symptoms, past current guideline recommendations of 20 days for length of isolation in immunocompromised patients. Whole genome sequencing of their viruses was performed to ascertain the transmission. Discussion: Severely immunocompromised patients, whose clearance of the virus is impaired, may remain infectious for extended periods. Caution should be taken particularly in hospital settings where lapses in isolation procedures might pose increased risk, especially to other immunocompromised patients.

Original languageEnglish
Pages (from-to)880-882
JournalInfectious diseases
Issue number11
Publication statusPublished - 2021
Publication typeB1 Journal article


  • Covid
  • immunosuppression
  • late shedding
  • SARS-CoV-2
  • transmission

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases


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