Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons

Ludovic Mayer; Abdallah Slablab; Géraldine Dantelle; Vincent Jacques; Aude Marie Lepagnol-Bestel; Sandrine Perruchas; Piernicola Spinicelli; Alice Thomas; Dominique Chauvat; Michel Simonneau; Thierry Gacoin; Jean François Roch

doi:10.1039/c3nr01251d

Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons

Ludovic Mayer
, Abdallah Slablab
, Géraldine Dantelle
, Vincent Jacques
, Aude Marie Lepagnol-Bestel
, Sandrine Perruchas
, Piernicola Spinicelli
, Alice Thomas
, Dominique Chauvat
, Michel Simonneau
, Thierry Gacoin^*
, Jean François Roch

^*Corresponding author for this work

Research output: Contribution to journal › Article › Scientific › peer-review

38 Citations (Scopus)

Abstract

We report an efficient colloidal synthesis of KTiOPO₄ (KTP) nanocrystals with excellent crystallinity and the direct observation of optical second-harmonic generation (SHG) from discrete KTP nanocrystals in neurons cultured from mammalian brain cortex. Direct internalization and monitoring of these nanoparticles was successfully achieved without limitations from cytotoxicity, bleaching and blinking emission.

Original language	English
Pages (from-to)	8466-8471
Number of pages	6
Journal	Nanoscale
Volume	5
Issue number	18
DOIs	https://doi.org/10.1039/c3nr01251d
Publication status	Published - 21 Sept 2013
Publication type	A1 Journal article-refereed

Publication forum classification

Publication forum level 1

ASJC Scopus subject areas

General Materials Science
General Medicine

Access to Document

10.1039/c3nr01251d

Cite this

@article{bb618c5f237f42568e77b66996029784,

title = "Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons",

abstract = "We report an efficient colloidal synthesis of KTiOPO4 (KTP) nanocrystals with excellent crystallinity and the direct observation of optical second-harmonic generation (SHG) from discrete KTP nanocrystals in neurons cultured from mammalian brain cortex. Direct internalization and monitoring of these nanoparticles was successfully achieved without limitations from cytotoxicity, bleaching and blinking emission.",

author = "Ludovic Mayer and Abdallah Slablab and G{\'e}raldine Dantelle and Vincent Jacques and Lepagnol-Bestel, \{Aude Marie\} and Sandrine Perruchas and Piernicola Spinicelli and Alice Thomas and Dominique Chauvat and Michel Simonneau and Thierry Gacoin and Roch, \{Jean Fran{\c c}ois\}",

year = "2013",

month = sep,

day = "21",

doi = "10.1039/c3nr01251d",

language = "English",

volume = "5",

pages = "8466--8471",

journal = "Nanoscale",

issn = "2040-3364",

publisher = "Royal Society of Chemistry",

number = "18",

}

TY - JOUR

T1 - Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons

AU - Mayer, Ludovic

AU - Slablab, Abdallah

AU - Dantelle, Géraldine

AU - Jacques, Vincent

AU - Lepagnol-Bestel, Aude Marie

AU - Perruchas, Sandrine

AU - Spinicelli, Piernicola

AU - Thomas, Alice

AU - Chauvat, Dominique

AU - Simonneau, Michel

AU - Gacoin, Thierry

AU - Roch, Jean François

PY - 2013/9/21

Y1 - 2013/9/21

N2 - We report an efficient colloidal synthesis of KTiOPO4 (KTP) nanocrystals with excellent crystallinity and the direct observation of optical second-harmonic generation (SHG) from discrete KTP nanocrystals in neurons cultured from mammalian brain cortex. Direct internalization and monitoring of these nanoparticles was successfully achieved without limitations from cytotoxicity, bleaching and blinking emission.

AB - We report an efficient colloidal synthesis of KTiOPO4 (KTP) nanocrystals with excellent crystallinity and the direct observation of optical second-harmonic generation (SHG) from discrete KTP nanocrystals in neurons cultured from mammalian brain cortex. Direct internalization and monitoring of these nanoparticles was successfully achieved without limitations from cytotoxicity, bleaching and blinking emission.

UR - https://www.scopus.com/pages/publications/84883180939

U2 - 10.1039/c3nr01251d

DO - 10.1039/c3nr01251d

M3 - Article

C2 - 23852161

AN - SCOPUS:84883180939

SN - 2040-3364

VL - 5

SP - 8466

EP - 8471

JO - Nanoscale

JF - Nanoscale

IS - 18

ER -

Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons

Abstract

Publication forum classification

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this