TY - JOUR
T1 - Social functioning in adults born very preterm
T2 - Individual participant meta-analysis
AU - Ni, Yanyan
AU - Mendonça, Marina
AU - Baumann, Nicole
AU - Eves, Robert
AU - Kajantie, Eero
AU - Hovi, Petteri
AU - Tikanmaki, Marjaana
AU - Raikkonen, Katri
AU - Heinonen, Kati
AU - Indredavik, Marit S.
AU - Evensen, Kari Anne I.
AU - Johnson, Samantha
AU - Marlow, Neil
AU - Wolke, Dieter
N1 - Funding Information:
Accepted for publication July 22, 2021 Address correspondence to Dieter Wolke, PhD, Department of Psychology, University of Warwick, Coventry CV4 7AL, United Kingdom. E-mail: [email protected] PEDIATRICS (ISSN Numbers: Print, 0031-4005; Online, 1098-4275). Copyright © 2021 by the American Academy of Pediatrics FINANCIAL DISCLOSURES: Dr Marlow declares consultancy fees from RSM Consulting, Takeda, and Novartis in the past 3 years outside this study. The other authors indicated they have no conflicts of interest to disclose. FUNDING: Funded by the European Union’s Horizon 2020 Research and Innovation Program (grant 733280). The funder did not participate in the work. POTENTIAL CONFLICT OF INTEREST: Dr Marlow declares consultancy fees from RSM Consulting, Takeda, and Novartis in the past 3 years outside this study. The other authors have indicated they have no potential conflicts of interest to disclose.
Publisher Copyright:
Copyright © 2021 by the American Academy of Pediatrics
PY - 2021
Y1 - 2021
N2 - CONTEXT: There is a lack of research on individual perceptions of social experiences and social relationships among very preterm (VP) adults compared with term-born peers. OBJECTIVE: To investigate self-perceived social functioning in adults born VP (<32 weeks’ gestation) and/or with very low birth weight (VLBW) (<1500g) compared with term-born adults ($37 weeks’ gestation) using an individual participant data (IPD) meta-analysis. DATA SOURCES: Two international consortia: Research on European Children and Adults born Preterm and Adults Born Preterm International Collaboration. STUDY SELECTION: Cohorts with outcomes assessed by using the Adult Self-Report Adaptive Functioning scales (friends, spouse/partner, family, job, and education) in both groups. DATA EXTRACTION: IPD from 5 eligible cohorts were collected. Raw-sum scores for each scale were standardized as z scores by using mean and SD of controls for each cohort. Pooled effect size was measured by difference (D) in means between groups. RESULTS: One-stage analyses (1285 participants) revealed significantly lower scores for relationships with friends in VP/VLBW adults compared with controls (D -0.37, 95% confidence interval [CI]: -0.61 to -0.13). Differences were similar after adjusting for sex, age, and socioeconomic status (D -0.39, 95% CI: -0.63 to -0.15) and after excluding participants with neurosensory impairment (D -0.34, 95% CI: -0.61 to -0.07). No significant differences were found in other domains. LIMITATIONS: Generalizability of research findings to VP survivors born in recent decades. CONCLUSIONS: VP/VLBW adults scored their relationship with friends lower but perceived their family and partner relationships, as well as work and educational experiences, as comparable to those of controls.
AB - CONTEXT: There is a lack of research on individual perceptions of social experiences and social relationships among very preterm (VP) adults compared with term-born peers. OBJECTIVE: To investigate self-perceived social functioning in adults born VP (<32 weeks’ gestation) and/or with very low birth weight (VLBW) (<1500g) compared with term-born adults ($37 weeks’ gestation) using an individual participant data (IPD) meta-analysis. DATA SOURCES: Two international consortia: Research on European Children and Adults born Preterm and Adults Born Preterm International Collaboration. STUDY SELECTION: Cohorts with outcomes assessed by using the Adult Self-Report Adaptive Functioning scales (friends, spouse/partner, family, job, and education) in both groups. DATA EXTRACTION: IPD from 5 eligible cohorts were collected. Raw-sum scores for each scale were standardized as z scores by using mean and SD of controls for each cohort. Pooled effect size was measured by difference (D) in means between groups. RESULTS: One-stage analyses (1285 participants) revealed significantly lower scores for relationships with friends in VP/VLBW adults compared with controls (D -0.37, 95% confidence interval [CI]: -0.61 to -0.13). Differences were similar after adjusting for sex, age, and socioeconomic status (D -0.39, 95% CI: -0.63 to -0.15) and after excluding participants with neurosensory impairment (D -0.34, 95% CI: -0.61 to -0.07). No significant differences were found in other domains. LIMITATIONS: Generalizability of research findings to VP survivors born in recent decades. CONCLUSIONS: VP/VLBW adults scored their relationship with friends lower but perceived their family and partner relationships, as well as work and educational experiences, as comparable to those of controls.
U2 - 10.1542/peds.2021-051986
DO - 10.1542/peds.2021-051986
M3 - Review Article
AN - SCOPUS:85118617805
SN - 0031-4005
VL - 148
JO - Pediatrics
JF - Pediatrics
IS - 5
M1 - e2021051986
ER -