Somatostatin-like immunoreactivity in human sympathetic ganglia

Riitta Järvi, Markku Pelto-Huikko, Pauli Helen, Antti Hervonen

Research output: Contribution to journalArticleScientificpeer-review

17 Citations (Scopus)


The localization of somatostatin-like immunore-activity (SOM-LI) was examined in human lumbar sympathetic ganglia using the peroxidase-antiperoxidase method. Few of the principal neurons showed immunolabelling for somatostatin and sparse networks of nerve terminals were unevenly associated with ganglion cells. Using light microscopy, the most intense SOM-LI was seen in the perinuclear zone of the neurons. Electron-microscopically, the staining was localized on the membranes of the Golgi apparatuses. In the nerve terminals, SOM-LI was seen inside the small vesicles (40-60 nm diameter). All neurons with SOM-LI were also found to be tyrosine-hydroxylase immunoreactive when excamined with a double-staining technique. These results provide evidence that somatostatin and noradrenaline co-exist in human sympathetic neurons.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
Issue number1
Publication statusPublished - Jul 1987
Externally publishedYes
Publication typeA1 Journal article-refereed


  • Co-existence
  • Human
  • Immunocytochemistry
  • Somatostatin
  • Sympathetic ganglion
  • Tyrosine hydroxylase

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Cell Biology


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