Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases

Joshua B. Sheetz; Steven E. Stayrook; Yuko Tsutsui; Ravi Radhakrishnan; Daniela Ungureanu; Stefan Knapp; Mark A. Lemmon; Sebastian Mathea; Hanna Karvonen; Ketan Malhotra; Deep Chatterjee; Wilhelmiina Niininen; Robert Perttilä; Franziska Preuss; Krishna Suresh

doi:10.1016/j.molcel.2020.06.018

Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases

Joshua B. Sheetz
, Steven E. Stayrook
, Yuko Tsutsui
, Ravi Radhakrishnan
, Daniela Ungureanu
, Stefan Knapp
, Mark A. Lemmon
, Sebastian Mathea
, Hanna Karvonen
, Ketan Malhotra
, Deep Chatterjee
, Wilhelmiina Niininen
, Robert Perttilä
, Franziska Preuss
, Krishna Suresh

Research output: Contribution to journal › Article › Scientific › peer-review

85 Citations (Scopus)

Original language	English
Pages (from-to)	390-405
Journal	Molecular Cell
Volume	79
Issue number	3
DOIs	https://doi.org/10.1016/j.molcel.2020.06.018
Publication status	Published - 2020
Publication type	A1 Journal article-refereed

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

GZD824
Wnt signaling
cancer
growth factor signaling
ponatinib
protein conformation
pseudokinases
receptor tyrosine kinases
targeted therapies

Publication forum classification

Publication forum level 3

Access to Document

10.1016/j.molcel.2020.06.018

http://urn.fi/URN:NBN:fi:tuni-202009257126

Cite this

Sheetz, J. B., Stayrook, S. E., Tsutsui, Y., Radhakrishnan, R., Ungureanu, D., Knapp, S., Lemmon, M. A., Mathea, S., Karvonen, H., Malhotra, K., Chatterjee, D., Niininen, W., Perttilä, R., Preuss, F., & Suresh, K. (2020). Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases. Molecular Cell, 79(3), 390-405. https://doi.org/10.1016/j.molcel.2020.06.018

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AU - Tsutsui, Yuko

AU - Radhakrishnan, Ravi

AU - Ungureanu, Daniela

AU - Knapp, Stefan

AU - Lemmon, Mark A.

AU - Mathea, Sebastian

AU - Karvonen, Hanna

AU - Malhotra, Ketan

AU - Chatterjee, Deep

AU - Niininen, Wilhelmiina

AU - Perttilä, Robert

AU - Preuss, Franziska

AU - Suresh, Krishna

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KW - ponatinib

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KW - pseudokinases

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KW - Wnt signaling

KW - cancer

KW - growth factor signaling

KW - ponatinib

KW - protein conformation

KW - pseudokinases

KW - receptor tyrosine kinases

KW - targeted therapies

U2 - 10.1016/j.molcel.2020.06.018

DO - 10.1016/j.molcel.2020.06.018

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JO - Molecular Cell

JF - Molecular Cell

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