TY - JOUR
T1 - Surgical and functional outcomes and survival following Colon Cancer surgery in the aged
T2 - a study protocol for a prospective, observational multicentre study
AU - Niemeläinen, Susanna
AU - Huhtala, Heini
AU - Ehrlich, Anu
AU - Kössi, Jyrki
AU - Jämsen, Esa
AU - Hyöty, Marja
N1 - Funding Information:
This study is financially partly supported by the Competitive State Research Financing of the Expert Responsibility area of Tampere University Hospital. Cancer Foundation Finland obtained external funding by awarding a grant, but they did not have any role in designing of the study, collection, analysis, interpretation of the data or writing the manuscript.
Publisher Copyright:
© 2021, The Author(s).
PY - 2021
Y1 - 2021
N2 - Background: The number of colorectal cancer patients increases with age. The decision to go through major surgery can be challenging for the aged patient and the surgeon because of the heterogeneity within the older population. Differences in preoperative physical and cognitive status can affect postoperative outcomes and functional recovery, and impact on patients’ quality of life. Methods / design: A prospective, observational, multicentre study including nine hospitals to analyse the impact of colon cancer surgery on functional ability, short-term outcomes (complications and mortality), and their predictors in patients aged ≥80 years. The catchment area of the study hospitals is 3.88 million people, representing 70% of the population of Finland. The data will be gathered from patient baseline characteristics, surgical interventional data, and pre- and postoperative patient-questionnaires, to an electronic database (REDCap) especially dedicated to the study. Discussion: This multicentre study provides information about colon cancer surgery’s operative and functional outcomes on older patients. A further aim is to find prognostic factors which could help to predict adverse outcomes of surgery. Trial registration: ClinicalTrials.gov (NCT03904121). Registered on 1 April 2019.
AB - Background: The number of colorectal cancer patients increases with age. The decision to go through major surgery can be challenging for the aged patient and the surgeon because of the heterogeneity within the older population. Differences in preoperative physical and cognitive status can affect postoperative outcomes and functional recovery, and impact on patients’ quality of life. Methods / design: A prospective, observational, multicentre study including nine hospitals to analyse the impact of colon cancer surgery on functional ability, short-term outcomes (complications and mortality), and their predictors in patients aged ≥80 years. The catchment area of the study hospitals is 3.88 million people, representing 70% of the population of Finland. The data will be gathered from patient baseline characteristics, surgical interventional data, and pre- and postoperative patient-questionnaires, to an electronic database (REDCap) especially dedicated to the study. Discussion: This multicentre study provides information about colon cancer surgery’s operative and functional outcomes on older patients. A further aim is to find prognostic factors which could help to predict adverse outcomes of surgery. Trial registration: ClinicalTrials.gov (NCT03904121). Registered on 1 April 2019.
KW - Aged patients
KW - Colon cancer
KW - Functional ability, short-term outcome
KW - Surgery
U2 - 10.1186/s12885-021-08454-8
DO - 10.1186/s12885-021-08454-8
M3 - Article
C2 - 34126949
AN - SCOPUS:85107851289
SN - 1471-2407
VL - 21
JO - BMC Cancer
JF - BMC Cancer
IS - 1
M1 - 698
ER -
