Surgical strategies for chronic pancreatitis in a 1,327- patient Scandinavian Baltic pancreatic Club (SBPC) register

Scandinavian Baltic Pancreatic Club, Mikael Parhiala, Anne Waage, Povilas Ignatavičius, Søren S. Olesen, Jakob L. Poulsen, Engjom Trond, Georg Dimcevski, Ingrid Nordaas, Amer Hadi, Evangelos Kalaitzakis, Asbjørn M. Drewes, Camilla Nøjgaard, Johanna Laukkarinen

    Research output: Contribution to journalArticleScientificpeer-review

    3 Citations (Scopus)

    Abstract

    Background: Chronic pancreatitis (CP) may cause intermittent or continuous pain and complications requiring invasive interventions. No specific recommendations for surgical interventions have been presented. Our aim was to determine the surgical treatment strategies for the treatment of CP in the Scandinavian and Baltic countries. Methods: This multi-centre cross sectional study included 1327 CP patients from eight centres. The data was gathered from the Scandinavian Baltic Pancreatic Club (SBPC) database. Patients who underwent pancreatic surgery were analysed. The baseline CP population from the eight centres was used as a reference. The information registered included comorbidities, pancreatic function, previous interventions, time and type of surgery and the EORTC-30 quality of life (QOL) questionnaire. Results: Overall, 95/1327 (7%) patients underwent pancreatic surgery. Fifty-one (54%) of these underwent pancreatic surgery for chronic pain (PSCP) and formed the final study group. Median follow-up time was two (range 0–8) years after surgery and seven (1–46) years after diagnosis. The most common surgical procedures were pancreatic resection combined with drainage (54%) followed by pancreatic resections (32%) and drainage procedures (14%). Postoperatively, 47% of the patients were pain free with or without pain medication while 16% had chronic pain episodes, this did not differ from the base CP population. In QOL questionnaires, PSCP patients reported the same QOL but worse social functioning and more symptoms compared to the CP population. Conclusions: Pancreatic surgery for CP is rare: surgical procedures were performed on only 7% of the CP patients in the SBPC database. In half of the patients the indication was pain. Most of these patients underwent endoscopic procedures before surgery. Half of the patients reported being pain-free after surgery.

    Original languageEnglish
    Pages (from-to)28-34
    JournalPancreatology
    Volume23
    Issue number1
    Early online date11 Dec 2022
    DOIs
    Publication statusPublished - Jan 2023
    Publication typeA1 Journal article-refereed

    Keywords

    • Chronic pancreatitis
    • Pain
    • Quality of life
    • Surgery

    Publication forum classification

    • Publication forum level 1

    ASJC Scopus subject areas

    • Endocrinology, Diabetes and Metabolism
    • Hepatology
    • Gastroenterology

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