Synthesis and Anticancer Properties of Fucoidan-Mimetic Glycopolymer Coated Gold Nanoparticles

Mattias Tengdelius, Deepanjali Gurav, Peter Konradsson, Peter Påhlsson, May Griffith, Oommen P. Oommen

    Research output: Contribution to journalArticleScientificpeer-review

    31 Citations (Scopus)
    36 Downloads (Pure)

    Abstract

    Gold nanoparticles coated with fucoidan-mimetic glycopolymers were
    synthesized that displayed good colloidal stability and promising anticancer
    properties. Fucoidan mimetic glycopolymers on their own were
    nontoxic, while glycopolymer coated gold nanoparticles displayed
    selective cytotoxicity to human colon cancer cell lines (HCT116) while
    it was non-toxic to mouse fibroblast cells (NIH3T3).
    Original languageEnglish
    Pages (from-to)8532-8535
    JournalChemical Communications
    Volume51
    Issue number40
    DOIs
    Publication statusPublished - 10 Apr 2015
    Publication typeA1 Journal article-refereed

    Publication forum classification

    • Publication forum level 2

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