T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence

Pihla Pakkanen; Taru Ilmarinen; Elina Halme; Heikki Irjala; Petri Koivunen; Matti Pukkila; Sami Ventelä; Jaana Hagström; Leena Maija Aaltonen

doi:10.1007/s00405-021-06983-3

T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence

Pihla Pakkanen, Taru Ilmarinen, Elina Halme, Heikki Irjala, Petri Koivunen, Matti Pukkila, Sami Ventelä, Jaana Hagström, Leena Maija Aaltonen

Research output: Contribution to journal › Article › Scientific › peer-review

6 Citations (Scopus)

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Abstract

Purpose: We assessed the treatment outcome and the benefits of routine follow-up visits in T1 glottic laryngeal squamous cell carcinoma (LSCC). Methods: Medical records of patients diagnosed with stage T1 glottic LSCC (N = 303) in five Finnish university hospitals between 2003 and 2015 were reviewed. Moreover, data from the Finnish Cancer Registry and the Population Register Center were collected. Results: Of all 38 recurrences, 26 (68%) were detected during a routine follow-up visit, and over half (21 of 38, 55%) presented without new symptoms. Primary treatment method (surgery vs. radiotherapy) was not connected with 5-year disease-specific survival (DSS) or laryngeal preservation rate. Conclusion: The majority of recurrences were detected on a routine follow-up visit, and local recurrences often presented without new symptoms. Routine post-treatment follow-up of T1 glottic LSCC seems beneficial. Trial registration: Trial registration number and date of registration HUS/356/2017 11.12.2017.

Original language	English
Journal	European Archives of Oto-Rhino-Laryngology
DOIs	https://doi.org/10.1007/s00405-021-06983-3
Publication status	E-pub ahead of print - 6 Aug 2021
Publication type	A1 Journal article-refereed

Funding

Open access funding provided by University of Helsinki including Helsinki University Central Hospital. The study was funded by Helsinki University Hospital research funds.

Keywords

Early laryngeal cancer
Follow-up
Glottic cancer
Recurrence
Treatment method

Publication forum classification

Publication forum level 1

ASJC Scopus subject areas

Otorhinolaryngology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00405-021-06983-3

Pakkanen2021_Article_T1GlotticLaryngealCancerTheRol
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Final published version, 700 KBLicence: CC BY

http://urn.fi/URN:NBN:fi:tuni-202109087010Licence: CC BY

Cite this

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title = "T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence",

abstract = "Purpose: We assessed the treatment outcome and the benefits of routine follow-up visits in T1 glottic laryngeal squamous cell carcinoma (LSCC). Methods: Medical records of patients diagnosed with stage T1 glottic LSCC (N = 303) in five Finnish university hospitals between 2003 and 2015 were reviewed. Moreover, data from the Finnish Cancer Registry and the Population Register Center were collected. Results: Of all 38 recurrences, 26 (68%) were detected during a routine follow-up visit, and over half (21 of 38, 55%) presented without new symptoms. Primary treatment method (surgery vs. radiotherapy) was not connected with 5-year disease-specific survival (DSS) or laryngeal preservation rate. Conclusion: The majority of recurrences were detected on a routine follow-up visit, and local recurrences often presented without new symptoms. Routine post-treatment follow-up of T1 glottic LSCC seems beneficial. Trial registration: Trial registration number and date of registration HUS/356/2017 11.12.2017.",

keywords = "Early laryngeal cancer, Follow-up, Glottic cancer, Recurrence, Treatment method",

author = "Pihla Pakkanen and Taru Ilmarinen and Elina Halme and Heikki Irjala and Petri Koivunen and Matti Pukkila and Sami Ventel{\"a} and Jaana Hagstr{\"o}m and Aaltonen, {Leena Maija}",

note = "Funding Information: Open access funding provided by University of Helsinki including Helsinki University Central Hospital. The study was funded by Helsinki University Hospital research funds. Publisher Copyright: {\textcopyright} 2021, The Author(s).",

year = "2021",

month = aug,

day = "6",

doi = "10.1007/s00405-021-06983-3",

language = "English",

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TY - JOUR

T1 - T1 glottic laryngeal cancer

T2 - the role of routine follow-up visits in detecting local recurrence

AU - Pakkanen, Pihla

AU - Ilmarinen, Taru

AU - Halme, Elina

AU - Irjala, Heikki

AU - Koivunen, Petri

AU - Pukkila, Matti

AU - Ventelä, Sami

AU - Hagström, Jaana

AU - Aaltonen, Leena Maija

N1 - Funding Information: Open access funding provided by University of Helsinki including Helsinki University Central Hospital. The study was funded by Helsinki University Hospital research funds. Publisher Copyright: © 2021, The Author(s).

PY - 2021/8/6

Y1 - 2021/8/6

N2 - Purpose: We assessed the treatment outcome and the benefits of routine follow-up visits in T1 glottic laryngeal squamous cell carcinoma (LSCC). Methods: Medical records of patients diagnosed with stage T1 glottic LSCC (N = 303) in five Finnish university hospitals between 2003 and 2015 were reviewed. Moreover, data from the Finnish Cancer Registry and the Population Register Center were collected. Results: Of all 38 recurrences, 26 (68%) were detected during a routine follow-up visit, and over half (21 of 38, 55%) presented without new symptoms. Primary treatment method (surgery vs. radiotherapy) was not connected with 5-year disease-specific survival (DSS) or laryngeal preservation rate. Conclusion: The majority of recurrences were detected on a routine follow-up visit, and local recurrences often presented without new symptoms. Routine post-treatment follow-up of T1 glottic LSCC seems beneficial. Trial registration: Trial registration number and date of registration HUS/356/2017 11.12.2017.

AB - Purpose: We assessed the treatment outcome and the benefits of routine follow-up visits in T1 glottic laryngeal squamous cell carcinoma (LSCC). Methods: Medical records of patients diagnosed with stage T1 glottic LSCC (N = 303) in five Finnish university hospitals between 2003 and 2015 were reviewed. Moreover, data from the Finnish Cancer Registry and the Population Register Center were collected. Results: Of all 38 recurrences, 26 (68%) were detected during a routine follow-up visit, and over half (21 of 38, 55%) presented without new symptoms. Primary treatment method (surgery vs. radiotherapy) was not connected with 5-year disease-specific survival (DSS) or laryngeal preservation rate. Conclusion: The majority of recurrences were detected on a routine follow-up visit, and local recurrences often presented without new symptoms. Routine post-treatment follow-up of T1 glottic LSCC seems beneficial. Trial registration: Trial registration number and date of registration HUS/356/2017 11.12.2017.

KW - Early laryngeal cancer

KW - Follow-up

KW - Glottic cancer

KW - Recurrence

KW - Treatment method

U2 - 10.1007/s00405-021-06983-3

DO - 10.1007/s00405-021-06983-3

M3 - Article

AN - SCOPUS:85112078063

SN - 0937-4477

JO - European Archives of Oto-Rhino-Laryngology

JF - European Archives of Oto-Rhino-Laryngology

ER -

T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence

Abstract

Funding

Keywords

Publication forum classification

ASJC Scopus subject areas

UN SDGs

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