T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence

Pihla Pakkanen; Taru Ilmarinen; Elina Halme; Heikki Irjala; Petri Koivunen; Matti Pukkila; Sami Ventelä; Jaana Hagström; Leena Maija Aaltonen

doi:10.1007/s00405-021-06983-3

T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence

Pihla Pakkanen^*
, Taru Ilmarinen
, Elina Halme
, Heikki Irjala
, Petri Koivunen
, Matti Pukkila
, Sami Ventelä
, Jaana Hagström
, Leena Maija Aaltonen

^*Corresponding author for this work

Research output: Contribution to journal › Article › Scientific › peer-review

12 Citations (Scopus)

16 Downloads (Pure)

Abstract

Purpose: We assessed the treatment outcome and the benefits of routine follow-up visits in T1 glottic laryngeal squamous cell carcinoma (LSCC). Methods: Medical records of patients diagnosed with stage T1 glottic LSCC (N = 303) in five Finnish university hospitals between 2003 and 2015 were reviewed. Moreover, data from the Finnish Cancer Registry and the Population Register Center were collected. Results: Of all 38 recurrences, 26 (68%) were detected during a routine follow-up visit, and over half (21 of 38, 55%) presented without new symptoms. Primary treatment method (surgery vs. radiotherapy) was not connected with 5-year disease-specific survival (DSS) or laryngeal preservation rate. Conclusion: The majority of recurrences were detected on a routine follow-up visit, and local recurrences often presented without new symptoms. Routine post-treatment follow-up of T1 glottic LSCC seems beneficial. Trial registration: Trial registration number and date of registration HUS/356/2017 11.12.2017.

Original language	English
Pages (from-to)	4863-4869
Journal	European Archives of Oto-Rhino-Laryngology
Volume	278
Issue number	12
DOIs	https://doi.org/10.1007/s00405-021-06983-3
Publication status	Published - Dec 2021
Publication type	A1 Journal article-refereed

Funding

Open access funding provided by University of Helsinki including Helsinki University Central Hospital. The study was funded by Helsinki University Hospital research funds.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Early laryngeal cancer
Follow-up
Glottic cancer
Recurrence
Treatment method

Publication forum classification

Publication forum level 1

ASJC Scopus subject areas

Otorhinolaryngology

Access to Document

10.1007/s00405-021-06983-3

Pakkanen2021_Article_T1GlotticLaryngealCancerTheRol
CC BY
Final published version, 700 KBLicence: CC BY

http://urn.fi/URN:NBN:fi:tuni-202109087010Licence: CC BY

Cite this

@article{28ece87e5c13478a96541e4acb8822ad,

title = "T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence",

abstract = "Purpose: We assessed the treatment outcome and the benefits of routine follow-up visits in T1 glottic laryngeal squamous cell carcinoma (LSCC). Methods: Medical records of patients diagnosed with stage T1 glottic LSCC (N = 303) in five Finnish university hospitals between 2003 and 2015 were reviewed. Moreover, data from the Finnish Cancer Registry and the Population Register Center were collected. Results: Of all 38 recurrences, 26 (68\%) were detected during a routine follow-up visit, and over half (21 of 38, 55\%) presented without new symptoms. Primary treatment method (surgery vs. radiotherapy) was not connected with 5-year disease-specific survival (DSS) or laryngeal preservation rate. Conclusion: The majority of recurrences were detected on a routine follow-up visit, and local recurrences often presented without new symptoms. Routine post-treatment follow-up of T1 glottic LSCC seems beneficial. Trial registration: Trial registration number and date of registration HUS/356/2017 11.12.2017.",

keywords = "Early laryngeal cancer, Follow-up, Glottic cancer, Recurrence, Treatment method",

author = "Pihla Pakkanen and Taru Ilmarinen and Elina Halme and Heikki Irjala and Petri Koivunen and Matti Pukkila and Sami Ventel{\"a} and Jaana Hagstr{\"o}m and Aaltonen, \{Leena Maija\}",

note = "Funding Information: Open access funding provided by University of Helsinki including Helsinki University Central Hospital. The study was funded by Helsinki University Hospital research funds. Publisher Copyright: {\textcopyright} 2021, The Author(s).",

year = "2021",

month = dec,

doi = "10.1007/s00405-021-06983-3",

language = "English",

volume = "278",

pages = "4863--4869",

journal = "European Archives of Oto-Rhino-Laryngology",

issn = "0937-4477",

publisher = "Springer",

number = "12",

}

TY - JOUR

T1 - T1 glottic laryngeal cancer

T2 - the role of routine follow-up visits in detecting local recurrence

AU - Pakkanen, Pihla

AU - Ilmarinen, Taru

AU - Halme, Elina

AU - Irjala, Heikki

AU - Koivunen, Petri

AU - Pukkila, Matti

AU - Ventelä, Sami

AU - Hagström, Jaana

AU - Aaltonen, Leena Maija

N1 - Funding Information: Open access funding provided by University of Helsinki including Helsinki University Central Hospital. The study was funded by Helsinki University Hospital research funds. Publisher Copyright: © 2021, The Author(s).

PY - 2021/12

Y1 - 2021/12

N2 - Purpose: We assessed the treatment outcome and the benefits of routine follow-up visits in T1 glottic laryngeal squamous cell carcinoma (LSCC). Methods: Medical records of patients diagnosed with stage T1 glottic LSCC (N = 303) in five Finnish university hospitals between 2003 and 2015 were reviewed. Moreover, data from the Finnish Cancer Registry and the Population Register Center were collected. Results: Of all 38 recurrences, 26 (68%) were detected during a routine follow-up visit, and over half (21 of 38, 55%) presented without new symptoms. Primary treatment method (surgery vs. radiotherapy) was not connected with 5-year disease-specific survival (DSS) or laryngeal preservation rate. Conclusion: The majority of recurrences were detected on a routine follow-up visit, and local recurrences often presented without new symptoms. Routine post-treatment follow-up of T1 glottic LSCC seems beneficial. Trial registration: Trial registration number and date of registration HUS/356/2017 11.12.2017.

AB - Purpose: We assessed the treatment outcome and the benefits of routine follow-up visits in T1 glottic laryngeal squamous cell carcinoma (LSCC). Methods: Medical records of patients diagnosed with stage T1 glottic LSCC (N = 303) in five Finnish university hospitals between 2003 and 2015 were reviewed. Moreover, data from the Finnish Cancer Registry and the Population Register Center were collected. Results: Of all 38 recurrences, 26 (68%) were detected during a routine follow-up visit, and over half (21 of 38, 55%) presented without new symptoms. Primary treatment method (surgery vs. radiotherapy) was not connected with 5-year disease-specific survival (DSS) or laryngeal preservation rate. Conclusion: The majority of recurrences were detected on a routine follow-up visit, and local recurrences often presented without new symptoms. Routine post-treatment follow-up of T1 glottic LSCC seems beneficial. Trial registration: Trial registration number and date of registration HUS/356/2017 11.12.2017.

KW - Early laryngeal cancer

KW - Follow-up

KW - Glottic cancer

KW - Recurrence

KW - Treatment method

U2 - 10.1007/s00405-021-06983-3

DO - 10.1007/s00405-021-06983-3

M3 - Article

AN - SCOPUS:85112078063

SN - 0937-4477

VL - 278

SP - 4863

EP - 4869

JO - European Archives of Oto-Rhino-Laryngology

JF - European Archives of Oto-Rhino-Laryngology

IS - 12

ER -

T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence

Abstract

Funding

UN SDGs

Keywords

Publication forum classification

ASJC Scopus subject areas

Access to Document

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