Temperature effect on the baseline noise in MEA measurements

    Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

    21 Downloads (Pure)

    Abstract

    It is a well known fact that increasing temperature increases noise in all kind of electronics, which applies also to cell and tissue measurements by microelectrode arrays (MEAs). We show that ambient temperature may have a surprisingly big role in the noise level of MEA measurements. To study that we measured the baseline noise when the MEA amplifier was subject to temperature variations, either in a temperature chamber or by preventing amplifier unit’s normal heat exchange. Around room temperature (+24°C) the RMS value of the baseline noise was found to increase approximately 0.14 µV/°C, which is a huge variation as the default RMS noise at that temperature with our setup was only around 5.5 µV. Additional cooling of the MEA amplifier could thus be a clever way to decrease the noise level at very sensitive measurements and on the other hand, one should not interfere the amplifier’s normal heat exchange to the ambient air in order to avoid additional warming and thus increasing the noise level.

    Original languageEnglish
    Title of host publicationEMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017
    PublisherSpringer Verlag
    Pages5-8
    Number of pages4
    ISBN (Print)9789811051210
    DOIs
    Publication statusPublished - 2018
    Publication typeA4 Article in a conference publication
    EventJoint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC) -
    Duration: 1 Jan 1900 → …

    Publication series

    NameIFMBE Proceedings
    Volume65
    ISSN (Print)1680-0737

    Conference

    ConferenceJoint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC)
    Period1/01/00 → …

    Keywords

    • MEA
    • Microelectrode array
    • Noise
    • Temperature

    Publication forum classification

    • Publication forum level 1

    ASJC Scopus subject areas

    • Biomedical Engineering
    • Bioengineering

    Fingerprint

    Dive into the research topics of 'Temperature effect on the baseline noise in MEA measurements'. Together they form a unique fingerprint.

    Cite this