Texture-property relations of bioamine crosslinked gellan gum hydrogels

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    Abstract

    Gellan gum is a hydrogel with potential for soft tissue engineering but a quick and thorough method is needed for screening of different possible compositions for more extensive studies. Here optical projection tomography in bright field mode was used to image nearly transparent hydrogels to record their optical texture in 3D. The gained Haralick’s textural features were then analyzed with multiple discriminant analysis and combined with data from mechanical testing and neuronal cell culturing. We show the usefulness of optical texture analysis in screening of hydrogel compositions when aiming for tissue engineering applications.

    Original languageEnglish
    Title of host publicationEMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017
    EditorsHannu Eskola
    PublisherSpringer Verlag
    Pages189-192
    Number of pages4
    ISBN (Print)978-981-10-5121-0
    DOIs
    Publication statusPublished - 2018
    Publication typeA4 Article in a conference publication
    EventJoint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC) -
    Duration: 1 Jan 2018 → …

    Publication series

    NameIFMBE Proceedings
    Volume65
    ISSN (Print)1433-9277

    Conference

    ConferenceJoint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC)
    Period1/01/18 → …

    Keywords

    • Gellan gum
    • Haralick's textural features
    • Haralick’s textural features
    • Hydrogel
    • Neuron
    • Optical projection tomography

    Publication forum classification

    • Publication forum level 1

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