The JH2 domain and SH2-JH2 linker regulate JAK2 activity: A detailed kinetic analysis of wild type and V617F mutant kinase domains

Arturo Sanz Sanz; A Sanz; Yashavanthi Niranjan; Henrik Hammarén; Daniela Ungureanu; Rob Ruijtenbeek; Ivo P Touw; Olli Silvennoinen; Riet Hilhorst

doi:10.1016/j.bbapap.2014.07.003

The JH2 domain and SH2-JH2 linker regulate JAK2 activity: A detailed kinetic analysis of wild type and V617F mutant kinase domains

Arturo Sanz Sanz, A Sanz, Yashavanthi Niranjan, Henrik Hammarén, Daniela Ungureanu, Rob Ruijtenbeek, Ivo P Touw, Olli Silvennoinen, Riet Hilhorst

Department of Internal medicine

Research output: Contribution to journal › Article › Scientific › peer-review

14 Citations (Scopus)

Original language	English
Pages (from-to)	1835-1841
Journal	Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
Volume	1844
Issue number	10
DOIs	https://doi.org/10.1016/j.bbapap.2014.07.003
Publication status	Published - 2014
Publication type	A1 Journal article-refereed

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10.1016/j.bbapap.2014.07.003

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Sanz Sanz, A., Sanz, A., Niranjan, Y., Hammarén, H., Ungureanu, D., Ruijtenbeek, R., Touw, I. P., Silvennoinen, O., & Hilhorst, R. (2014). The JH2 domain and SH2-JH2 linker regulate JAK2 activity: A detailed kinetic analysis of wild type and V617F mutant kinase domains. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1844(10), 1835-1841. https://doi.org/10.1016/j.bbapap.2014.07.003

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title = "The JH2 domain and SH2-JH2 linker regulate JAK2 activity: A detailed kinetic analysis of wild type and V617F mutant kinase domains",

author = "{Sanz Sanz}, Arturo and A Sanz and Yashavanthi Niranjan and Henrik Hammar{\'e}n and Daniela Ungureanu and Rob Ruijtenbeek and Touw, {Ivo P} and Olli Silvennoinen and Riet Hilhorst",

year = "2014",

doi = "10.1016/j.bbapap.2014.07.003",

language = "English",

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Sanz Sanz, A, Sanz, A, Niranjan, Y, Hammarén, H, Ungureanu, D, Ruijtenbeek, R, Touw, IP, Silvennoinen, O & Hilhorst, R 2014, 'The JH2 domain and SH2-JH2 linker regulate JAK2 activity: A detailed kinetic analysis of wild type and V617F mutant kinase domains', Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, vol. 1844, no. 10, pp. 1835-1841. https://doi.org/10.1016/j.bbapap.2014.07.003

The JH2 domain and SH2-JH2 linker regulate JAK2 activity: A detailed kinetic analysis of wild type and V617F mutant kinase domains. / Sanz Sanz, Arturo; Sanz, A; Niranjan, Yashavanthi et al.
In: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Vol. 1844, No. 10, 2014, p. 1835-1841.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - The JH2 domain and SH2-JH2 linker regulate JAK2 activity: A detailed kinetic analysis of wild type and V617F mutant kinase domains

AU - Sanz Sanz, Arturo

AU - Sanz, A

AU - Niranjan, Yashavanthi

AU - Hammarén, Henrik

AU - Ungureanu, Daniela

AU - Ruijtenbeek, Rob

AU - Touw, Ivo P

AU - Silvennoinen, Olli

AU - Hilhorst, Riet

PY - 2014

Y1 - 2014

U2 - 10.1016/j.bbapap.2014.07.003

DO - 10.1016/j.bbapap.2014.07.003

M3 - Article

VL - 1844

SP - 1835

EP - 1841

IS - 10

ER -