Abstract
We describe the fast reaction kinetics between 1,2-aminothiols and
aldehydes. Under physiological conditions such a click-type reaction
afforded a thiazolidine product that remains stable and did not
require any catalyst. This type of bioorthogonal reaction offers
enormous potential for the coupling of biomolecules in an efficient
and biocompatible manner
aldehydes. Under physiological conditions such a click-type reaction
afforded a thiazolidine product that remains stable and did not
require any catalyst. This type of bioorthogonal reaction offers
enormous potential for the coupling of biomolecules in an efficient
and biocompatible manner
Original language | English |
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Pages (from-to) | 12507-12510 |
Number of pages | 4 |
Journal | Chemical Communications |
DOIs | |
Publication status | Published - 15 Oct 2018 |
Publication type | A1 Journal article-refereed |
Publication forum classification
- Publication forum level 2