Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

Ming-Huei Chen; Laura Raffield; FM Raffield; Abdou Mousas; Saori Sakaue; Jennifer Huffman; Arden Moscati; Bhavi Trivedi; Tao Jiang; Parsa Akbari; Dragana Vuckovic; Erik Bao; Xue Zhong; Regina Manansala; Véronique Laplante; Minhui Chen; Ken Sin Lo; Huijun Qian; Caleb Lareau; Mélissa Beaudoin; Karen Hunt; Mika Kähönen; Terho Lehtimäki; Leo-Pekka Lyytikäinen; Nina Mononen; Kjell Nikus

doi:10.1016/j.cell.2020.06.045

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

Ming-Huei Chen, Laura Raffield, FM Raffield, Abdou Mousas, Saori Sakaue, Jennifer Huffman, Arden Moscati, Bhavi Trivedi, Tao Jiang, Parsa Akbari, Dragana Vuckovic, Erik Bao, Xue Zhong, Regina Manansala, Véronique Laplante, Minhui Chen, Ken Sin Lo, Huijun Qian, Caleb Lareau, Mélissa BeaudoinKaren Hunt, Mika Kähönen, Terho Lehtimäki, Leo-Pekka Lyytikäinen, Nina Mononen, Kjell Nikus

Research output: Contribution to journal › Article › Scientific › peer-review

329 Citations (Scopus)

Original language	English
Pages (from-to)	1198-1213
Journal	Cell
Volume	182
Issue number	5
DOIs	https://doi.org/10.1016/j.cell.2020.06.045
Publication status	Published - 2020
Publication type	A1 Journal article-refereed

Keywords

fine-mapping
genetic architecture
interleukin-7
phenome-wide association study
polygenic trait score
selective sweeps

Publication forum classification

Publication forum level 3

Access to Document

10.1016/j.cell.2020.06.045

Cite this

Chen, M.-H., Raffield, L., Raffield, FM., Mousas, A., Sakaue, S., Huffman, J., Moscati, A., Trivedi, B., Jiang, T., Akbari, P., Vuckovic, D., Bao, E., Zhong, X., Manansala, R., Laplante, V., Chen, M., Lo, K. S., Qian, H., Lareau, C., ... Nikus, K. (2020). Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Cell, 182(5), 1198-1213. https://doi.org/10.1016/j.cell.2020.06.045

@article{174abc1131d24730a760f1b72865c139,

title = "Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations",

keywords = "fine-mapping, genetic architecture, interleukin-7, phenome-wide association study, polygenic trait score, selective sweeps, fine-mapping, genetic architecture, interleukin-7, phenome-wide association study, polygenic trait score, selective sweeps",

author = "Ming-Huei Chen and Laura Raffield and FM Raffield and Abdou Mousas and Saori Sakaue and Jennifer Huffman and Arden Moscati and Bhavi Trivedi and Tao Jiang and Parsa Akbari and Dragana Vuckovic and Erik Bao and Xue Zhong and Regina Manansala and V{\'e}ronique Laplante and Minhui Chen and Lo, {Ken Sin} and Huijun Qian and Caleb Lareau and M{\'e}lissa Beaudoin and Karen Hunt and Mika K{\"a}h{\"o}nen and Terho Lehtim{\"a}ki and Leo-Pekka Lyytik{\"a}inen and Nina Mononen and Kjell Nikus",

year = "2020",

doi = "10.1016/j.cell.2020.06.045",

language = "English",

volume = "182",

pages = "1198--1213",

journal = "Cell",

issn = "0092-8674",

publisher = "Elsevier",

number = "5",

}

Chen, M-H, Raffield, L, Raffield, FM, Mousas, A, Sakaue, S, Huffman, J, Moscati, A, Trivedi, B, Jiang, T, Akbari, P, Vuckovic, D, Bao, E, Zhong, X, Manansala, R, Laplante, V, Chen, M, Lo, KS, Qian, H, Lareau, C, Beaudoin, M, Hunt, K, Kähönen, M , Lehtimäki, T , Lyytikäinen, L-P , Mononen, N & Nikus, K 2020, 'Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations', Cell, vol. 182, no. 5, pp. 1198-1213. https://doi.org/10.1016/j.cell.2020.06.045

TY - JOUR

T1 - Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

AU - Chen, Ming-Huei

AU - Raffield, Laura

AU - Raffield, FM

AU - Mousas, Abdou

AU - Sakaue, Saori

AU - Huffman, Jennifer

AU - Moscati, Arden

AU - Trivedi, Bhavi

AU - Jiang, Tao

AU - Akbari, Parsa

AU - Vuckovic, Dragana

AU - Bao, Erik

AU - Zhong, Xue

AU - Manansala, Regina

AU - Laplante, Véronique

AU - Chen, Minhui

AU - Lo, Ken Sin

AU - Qian, Huijun

AU - Lareau, Caleb

AU - Beaudoin, Mélissa

AU - Hunt, Karen

AU - Kähönen, Mika

AU - Lehtimäki, Terho

AU - Lyytikäinen, Leo-Pekka

AU - Mononen, Nina

AU - Nikus, Kjell

PY - 2020

Y1 - 2020

KW - fine-mapping

KW - genetic architecture

KW - interleukin-7

KW - phenome-wide association study

KW - polygenic trait score

KW - selective sweeps

KW - fine-mapping

KW - genetic architecture

KW - interleukin-7

KW - phenome-wide association study

KW - polygenic trait score

KW - selective sweeps

U2 - 10.1016/j.cell.2020.06.045

DO - 10.1016/j.cell.2020.06.045

M3 - Article

SN - 0092-8674

VL - 182

SP - 1198

EP - 1213

JO - Cell

JF - Cell

IS - 5

ER -