Unravelling the Relationship between Degree of Disorder and the Dissolution Behavior of Milled Glibenclamide

Pei T. Mah, Timo Laaksonen, Thomas Rades, Jaakko Aaltonen, Leena Peltonen, Clare J. Strachan

    Research output: Contribution to journalArticleScientificpeer-review

    20 Citations (Scopus)
    Original languageEnglish
    Pages (from-to)234-242
    Number of pages9
    JournalMolecular Pharmaceutics
    Volume11
    Issue number1
    DOIs
    Publication statusPublished - Jan 2014
    Publication typeA1 Journal article-refereed

    Keywords

    • amorphous
    • crystallinity
    • dissolution
    • glibenclamide
    • milling
    • recrystallization
    • XRPD
    • Raman spectroscopy
    • DSC
    • solid state analysis
    • CRYSTALLIZATION TENDENCY
    • AMORPHOUS INDOMETHACIN
    • PHYSICAL STABILITY
    • RAMAN-SPECTROSCOPY
    • UNDERCOOLED MELTS
    • THERMAL-BEHAVIOR
    • SOLUBLE DRUGS
    • AMORPHIZATION
    • GRISEOFULVIN
    • FORMULATION
    • 317 Pharmacy

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