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Unsupervised Algorithms for Microarray Sample Stratification

    Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

    3 Citations (Scopus)
    14 Downloads (Pure)

    Abstract

    The amount of data made available by microarrays gives researchers the opportunity to delve into the complexity of biological systems. However, the noisy and extremely high-dimensional nature of this kind of data poses significant challenges. Microarrays allow for the parallel measurement of thousands of molecular objects spanning different layers of interactions. In order to be able to discover hidden patterns, the most disparate analytical techniques have been proposed. Here, we describe the basic methodologies to approach the analysis of microarray datasets that focus on the task of (sub)group discovery.

    Original languageEnglish
    Title of host publicationMicroarray Data Analysis
    EditorsGiuseppe Agapito
    PublisherHumana Press
    Pages121-146
    Number of pages26
    ISBN (Electronic)978-1-0716-1839-4
    ISBN (Print)978-1-0716-1841-7
    DOIs
    Publication statusPublished - 2022
    Publication typeA3 Book chapter

    Publication series

    NameMethods in Molecular Biology
    Volume2401
    ISSN (Print)1064-3745
    ISSN (Electronic)1940-6029

    Keywords

    • Clustering
    • Dimensionality reduction
    • Group discovery
    • Microarray
    • Unsupervised learning

    Publication forum classification

    • Publication forum level 1

    ASJC Scopus subject areas

    • Molecular Biology
    • Genetics

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