Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

J.C. Bis; A.E. Renton; E. Marcora; J.J. Farrell; Y. Zhao; L. Qu; S. Ahmad; N. Amin; P. Amouyel; G.W. Beecham; J.E. Below; X. Jian; D. Campion; C. Charbonnier; J. Chung; P.K. Crane; C. Cruchaga; L.A. Cupples; J.-F. Dartigues; S. Debette; J.-F. Deleuze; L. Fulton; B.W. Kunkle; S.B. Gabriel; E. Genin; R.A. Gibbs; A. Goate; B. Grenier-Boley; N. Gupta; J.L. Haines; A.S. Havulinna; S. Helisalmi; M. Hiltunen; Y. Chen; D.P. Howrigan; M.A. Ikram; J. Kaprio; J. Konrad; A. Kuzma; E.S. Lander; Terho Lehtimäki; Kari Mattila; K.L. Hamilton-Nelson; W.S. Bush; W.J. Salerno; D. Lancour; Y. Ma

doi:10.1038/s41380-018-0112-7

Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

J.C. Bis, A.E. Renton, E. Marcora, J.J. Farrell, Y. Zhao, L. Qu, S. Ahmad, N. Amin, P. Amouyel, G.W. Beecham, J.E. Below, X. Jian, D. Campion, C. Charbonnier, J. Chung, P.K. Crane, C. Cruchaga, L.A. Cupples, J.-F. Dartigues, S. DebetteJ.-F. Deleuze, L. Fulton, B.W. Kunkle, S.B. Gabriel, E. Genin, R.A. Gibbs, A. Goate, B. Grenier-Boley, N. Gupta, J.L. Haines, A.S. Havulinna, S. Helisalmi, M. Hiltunen, Y. Chen, D.P. Howrigan, M.A. Ikram, J. Kaprio, J. Konrad, A. Kuzma, E.S. Lander, Terho Lehtimäki, Kari Mattila, K.L. Hamilton-Nelson, W.S. Bush, W.J. Salerno, D. Lancour, Y. Ma

Department of Clinical Chemistry

Research output: Contribution to journal › Article › Scientific › peer-review

62 Citations (Scopus)

Original language	English
Pages (from-to)	1859–1875
Journal	MOLECULAR PSYCHIATRY
Volume	25
Early online date	2018
DOIs	https://doi.org/10.1038/s41380-018-0112-7
Publication status	Published - 2020
Publication type	A1 Journal article-refereed

Publication forum classification

Publication forum level 3

Access to Document

10.1038/s41380-018-0112-7

http://urn.fi/URN:NBN:fi:tuni-202002112009

Cite this

Bis, J. C., Renton, A. E., Marcora, E., Farrell, J. J., Zhao, Y., Qu, L., Ahmad, S., Amin, N., Amouyel, P., Beecham, G. W., Below, J. E., Jian, X., Campion, D., Charbonnier, C., Chung, J., Crane, P. K., Cruchaga, C., Cupples, L. A., Dartigues, J-F., ... Ma, Y. (2020). Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. MOLECULAR PSYCHIATRY, 25, 1859–1875. https://doi.org/10.1038/s41380-018-0112-7

Bis, J.C. ; Renton, A.E. ; Marcora, E. ; Farrell, J.J. ; Zhao, Y. ; Qu, L. ; Ahmad, S. ; Amin, N. ; Amouyel, P. ; Beecham, G.W. ; Below, J.E. ; Jian, X. ; Campion, D. ; Charbonnier, C. ; Chung, J. ; Crane, P.K. ; Cruchaga, C. ; Cupples, L.A. ; Dartigues, J.-F. ; Debette, S. ; Deleuze, J.-F. ; Fulton, L. ; Kunkle, B.W. ; Gabriel, S.B. ; Genin, E. ; Gibbs, R.A. ; Goate, A. ; Grenier-Boley, B. ; Gupta, N. ; Haines, J.L. ; Havulinna, A.S. ; Helisalmi, S. ; Hiltunen, M. ; Chen, Y. ; Howrigan, D.P. ; Ikram, M.A. ; Kaprio, J. ; Konrad, J. ; Kuzma, A. ; Lander, E.S. ; Lehtimäki, Terho ; Mattila, Kari ; Hamilton-Nelson, K.L. ; Bush, W.S. ; Salerno, W.J. ; Lancour, D. ; Ma, Y. / Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. In: MOLECULAR PSYCHIATRY. 2020 ; Vol. 25. pp. 1859–1875.

@article{f22c5c0982274388a94bf9de6e068323,

title = "Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation",

author = "J.C. Bis and A.E. Renton and E. Marcora and J.J. Farrell and Y. Zhao and L. Qu and S. Ahmad and N. Amin and P. Amouyel and G.W. Beecham and J.E. Below and X. Jian and D. Campion and C. Charbonnier and J. Chung and P.K. Crane and C. Cruchaga and L.A. Cupples and J.-F. Dartigues and S. Debette and J.-F. Deleuze and L. Fulton and B.W. Kunkle and S.B. Gabriel and E. Genin and R.A. Gibbs and A. Goate and B. Grenier-Boley and N. Gupta and J.L. Haines and A.S. Havulinna and S. Helisalmi and M. Hiltunen and Y. Chen and D.P. Howrigan and M.A. Ikram and J. Kaprio and J. Konrad and A. Kuzma and E.S. Lander and Terho Lehtim{\"a}ki and Kari Mattila and K.L. Hamilton-Nelson and W.S. Bush and W.J. Salerno and D. Lancour and Y. Ma",

year = "2020",

doi = "10.1038/s41380-018-0112-7",

language = "English",

volume = "25",

pages = "1859–1875",

journal = "MOLECULAR PSYCHIATRY",

issn = "1359-4184",

publisher = "Nature Publishing Group",

}

Bis, JC, Renton, AE, Marcora, E, Farrell, JJ, Zhao, Y, Qu, L, Ahmad, S, Amin, N, Amouyel, P, Beecham, GW, Below, JE, Jian, X, Campion, D, Charbonnier, C, Chung, J, Crane, PK, Cruchaga, C, Cupples, LA, Dartigues, J-F, Debette, S, Deleuze, J-F, Fulton, L, Kunkle, BW, Gabriel, SB, Genin, E, Gibbs, RA, Goate, A, Grenier-Boley, B, Gupta, N, Haines, JL, Havulinna, AS, Helisalmi, S, Hiltunen, M, Chen, Y, Howrigan, DP, Ikram, MA, Kaprio, J, Konrad, J, Kuzma, A, Lander, ES, Lehtimäki, T , Mattila, K, Hamilton-Nelson, KL, Bush, WS, Salerno, WJ, Lancour, D & Ma, Y 2020, 'Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation', MOLECULAR PSYCHIATRY, vol. 25, pp. 1859–1875. https://doi.org/10.1038/s41380-018-0112-7

Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. / Bis, J.C.; Renton, A.E.; Marcora, E.; Farrell, J.J.; Zhao, Y.; Qu, L.; Ahmad, S.; Amin, N.; Amouyel, P.; Beecham, G.W.; Below, J.E.; Jian, X.; Campion, D.; Charbonnier, C.; Chung, J.; Crane, P.K.; Cruchaga, C.; Cupples, L.A.; Dartigues, J.-F.; Debette, S.; Deleuze, J.-F.; Fulton, L.; Kunkle, B.W.; Gabriel, S.B.; Genin, E.; Gibbs, R.A.; Goate, A.; Grenier-Boley, B.; Gupta, N.; Haines, J.L.; Havulinna, A.S.; Helisalmi, S.; Hiltunen, M.; Chen, Y.; Howrigan, D.P.; Ikram, M.A.; Kaprio, J.; Konrad, J.; Kuzma, A.; Lander, E.S.; Lehtimäki, Terho ; Mattila, Kari; Hamilton-Nelson, K.L.; Bush, W.S.; Salerno, W.J.; Lancour, D.; Ma, Y.

In: MOLECULAR PSYCHIATRY, Vol. 25, 2020, p. 1859–1875.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

AU - Bis, J.C.

AU - Renton, A.E.

AU - Marcora, E.

AU - Farrell, J.J.

AU - Zhao, Y.

AU - Qu, L.

AU - Ahmad, S.

AU - Amin, N.

AU - Amouyel, P.

AU - Beecham, G.W.

AU - Below, J.E.

AU - Jian, X.

AU - Campion, D.

AU - Charbonnier, C.

AU - Chung, J.

AU - Crane, P.K.

AU - Cruchaga, C.

AU - Cupples, L.A.

AU - Dartigues, J.-F.

AU - Debette, S.

AU - Deleuze, J.-F.

AU - Fulton, L.

AU - Kunkle, B.W.

AU - Gabriel, S.B.

AU - Genin, E.

AU - Gibbs, R.A.

AU - Goate, A.

AU - Grenier-Boley, B.

AU - Gupta, N.

AU - Haines, J.L.

AU - Havulinna, A.S.

AU - Helisalmi, S.

AU - Hiltunen, M.

AU - Chen, Y.

AU - Howrigan, D.P.

AU - Ikram, M.A.

AU - Kaprio, J.

AU - Konrad, J.

AU - Kuzma, A.

AU - Lander, E.S.

AU - Lehtimäki, Terho

AU - Mattila, Kari

AU - Hamilton-Nelson, K.L.

AU - Bush, W.S.

AU - Salerno, W.J.

AU - Lancour, D.

AU - Ma, Y.

PY - 2020

Y1 - 2020

U2 - 10.1038/s41380-018-0112-7

DO - 10.1038/s41380-018-0112-7

M3 - Article

VL - 25

SP - 1859

EP - 1875

JO - MOLECULAR PSYCHIATRY

JF - MOLECULAR PSYCHIATRY

SN - 1359-4184

ER -