Zonal segmentation of prostate using multispectral magnetic resonance images

N. Makni, A. Iancu, O. Colot, P. Puech, S. Mordon, N. Betrouni

    Research output: Contribution to journalArticleScientificpeer-review

    33 Citations (Scopus)


    Purpose: To investigate the performance of a new method of automatic segmentation of prostatic multispectral magnetic resonance images into two zones: the peripheral zone and the central gland. Methods: The proposed method is based on a modified version of the evidential C-means clustering algorithm. The evidential C-means optimization process was modified to introduce spatial neighborhood information. A priori knowledge of the prostate's zonal morphology was modeled as a geometric criterion and used as an additional data source to enhance the differentiation of the two zones. Results: Thirty-one clinical magnetic resonance imaging series were used to validate the method, and interobserver variability was taken into account in assessing its accuracy. The mean Dice Similarity Coefficient was 89 for the central gland and 80 for the peripheral zone, as validated by a consensus from expert radiologist segmentation. Conclusions: The method was statistically insensitive to variations in patient age, prostate volume and the presence of tumors, which increases its feasibility in a clinical context.

    Original languageEnglish
    Pages (from-to)6093-6105
    Number of pages13
    JournalMedical Physics
    Issue number11
    Publication statusPublished - Nov 2011
    Publication typeA1 Journal article-refereed


    • central gland
    • multispectral MRI
    • peripheral zone
    • prostate
    • Segmentation

    ASJC Scopus subject areas

    • Biophysics
    • Radiology Nuclear Medicine and imaging

    Fingerprint Dive into the research topics of 'Zonal segmentation of prostate using multispectral magnetic resonance images'. Together they form a unique fingerprint.

    Cite this