Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery

Oommen P. Varghese; Jianping Liu; Karthi Sundaram; Jöns Hilborn; Oommen Podiyan Oommen

doi:10.1039/c6bm00335d

Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery

Oommen P. Varghese
, Jianping Liu
, Karthi Sundaram
, Jöns Hilborn
, Oommen Podiyan Oommen

Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu

35 Sitaatiot (Scopus)

Abstrakti

Glycosaminoglycan derived nanoparticles are a promising delivery system owing to their unique tumour targeting ability. Exploiting fluorescein for inducing amphiphilicity in these biopolymers provides inherent imaging and drug stabilization capabilities by π-π stacking interactions with aromatic antineoplastic agents. This offers a versatile and highly customizable nanocarrier with narrow size distribution and high drug loading efficiency (80%) with sustained drug release.

Alkuperäiskieli	Englanti
Sivut	1310-1313
Sivumäärä	4
Julkaisu	Biomaterials Science
Vuosikerta	4
Numero	9
DOI - pysyväislinkit	https://doi.org/10.1039/c6bm00335d
Tila	Julkaistu - 1 syysk. 2016
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Julkaisufoorumi-taso

Jufo-taso 1

!!ASJC Scopus subject areas

Yleinen materiaalitiede
Biomedical Engineering

Pääsy asiakirjaan

10.1039/c6bm00335d

Siteeraa tätä

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title = "Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery",

abstract = "Glycosaminoglycan derived nanoparticles are a promising delivery system owing to their unique tumour targeting ability. Exploiting fluorescein for inducing amphiphilicity in these biopolymers provides inherent imaging and drug stabilization capabilities by π-π stacking interactions with aromatic antineoplastic agents. This offers a versatile and highly customizable nanocarrier with narrow size distribution and high drug loading efficiency (80\%) with sustained drug release.",

author = "Varghese, \{Oommen P.\} and Jianping Liu and Karthi Sundaram and J{\"o}ns Hilborn and \{Podiyan Oommen\}, Oommen",

year = "2016",

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doi = "10.1039/c6bm00335d",

language = "English",

volume = "4",

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journal = "Biomaterials Science",

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publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery

AU - Varghese, Oommen P.

AU - Liu, Jianping

AU - Sundaram, Karthi

AU - Hilborn, Jöns

AU - Podiyan Oommen, Oommen

PY - 2016/9/1

Y1 - 2016/9/1

N2 - Glycosaminoglycan derived nanoparticles are a promising delivery system owing to their unique tumour targeting ability. Exploiting fluorescein for inducing amphiphilicity in these biopolymers provides inherent imaging and drug stabilization capabilities by π-π stacking interactions with aromatic antineoplastic agents. This offers a versatile and highly customizable nanocarrier with narrow size distribution and high drug loading efficiency (80%) with sustained drug release.

AB - Glycosaminoglycan derived nanoparticles are a promising delivery system owing to their unique tumour targeting ability. Exploiting fluorescein for inducing amphiphilicity in these biopolymers provides inherent imaging and drug stabilization capabilities by π-π stacking interactions with aromatic antineoplastic agents. This offers a versatile and highly customizable nanocarrier with narrow size distribution and high drug loading efficiency (80%) with sustained drug release.

U2 - 10.1039/c6bm00335d

DO - 10.1039/c6bm00335d

M3 - Article

AN - SCOPUS:84983541733

SN - 2047-4830

VL - 4

SP - 1310

EP - 1313

JO - Biomaterials Science

JF - Biomaterials Science

IS - 9

ER -

Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery

Abstrakti

Julkaisufoorumi-taso

!!ASJC Scopus subject areas

Pääsy asiakirjaan

Sormenjälki

Siteeraa tätä