Crystal structure of an in vitro affinity- and specificity-matured anti-testosterone Fab in complex with testosterone. Improved affinity results from small structural changes within the variable domains

Jarkko Valjakka; Ari Hemminki; Seija Niemi; Hans Söderlund; Kristiina Takkinen; Juha Rouvinen

Crystal structure of an in vitro affinity- and specificity-matured anti-testosterone Fab in complex with testosterone. Improved affinity results from small structural changes within the variable domains

Jarkko Valjakka, Ari Hemminki, Seija Niemi, Hans Söderlund, Kristiina Takkinen, Juha Rouvinen

Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu

48 Sitaatiot (Scopus)

Alkuperäiskieli	Englanti
Sivut	44021-44027
Julkaisu	Journal of Biological Chemistry
Vuosikerta	Nov 15;277(46)
Tila	Julkaistu - 2002
Julkaistu ulkoisesti	Kyllä
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Siteeraa tätä

@article{ac420859bbce46caa8197d88836191f3,

title = "Crystal structure of an in vitro affinity- and specificity-matured anti-testosterone Fab in complex with testosterone. Improved affinity results from small structural changes within the variable domains",

author = "Jarkko Valjakka and Ari Hemminki and Seija Niemi and Hans S{\"o}derlund and Kristiina Takkinen and Juha Rouvinen",

year = "2002",

language = "English",

volume = "Nov 15;277(46)",

pages = "44021--44027",

journal = "Journal of Biological Chemistry",

issn = "0021-9258",

publisher = "American Society for Biochemistry and Molecular Biology",

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Crystal structure of an in vitro affinity- and specificity-matured anti-testosterone Fab in complex with testosterone. Improved affinity results from small structural changes within the variable domains. / Valjakka, Jarkko; Hemminki, Ari; Niemi, Seija et al.
julkaisussa: Journal of Biological Chemistry, Vuosikerta Nov 15;277(46), 2002, s. 44021-44027.

Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu

TY - JOUR

T1 - Crystal structure of an in vitro affinity- and specificity-matured anti-testosterone Fab in complex with testosterone. Improved affinity results from small structural changes within the variable domains

AU - Valjakka, Jarkko

AU - Hemminki, Ari

AU - Niemi, Seija

AU - Söderlund, Hans

AU - Takkinen, Kristiina

AU - Rouvinen, Juha

PY - 2002

Y1 - 2002

M3 - Article

SN - 0021-9258

VL - Nov 15;277(46)

SP - 44021

EP - 44027

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

ER -