Decane-1,2-diol derivatives as potential antitumor agents for the treatment of glioblastoma

Keyphrases

• Glioblastoma 100%
• Antitumor Agents 100%
• 1,2-Diols 100%
• Decane 100%
• Cytotoxicity 80%
• LN229 40%
• Hydrogen Bonds (H-bonds) 20%
• Synthetic Approaches 20%
• Glioma Cell Lines 20%
• Apoptosis 20%
• Sulfite 20%
• Esters 20%
• Diversity-oriented Synthesis 20%
• Caspase-3 20%
• Amino Acids 20%
• IC50 Value 20%
• Reactive Oxygen Species 20%
• Charged Residue 20%
• Transcriptional Level 20%
• Phosphonates 20%
• Glioblastoma Cell Lines 20%
• Anticancer Drugs 20%
• Sulfonate 20%
• N-methyl-D-aspartate Receptor (NMDAR) 20%
• Glioblastoma Cells 20%
• Cell Cycle Arrest 20%
• Primary Brain Tumor 20%
• Molecular Docking Studies 20%
• Antitumor Activity 20%
• Caspase-3/7 Activation 20%
• Apoptosis Induction 20%
• SCell 20%
• Residue Interaction 20%
• Caspase-dependent Apoptosis 20%
• Ketal 20%
• Cisplatin 20%
• Silyl Enol Ethers 20%
• Oxidative Stress 3 20%
• Antiproliferative Properties 20%
• Small Molecule Libraries 20%
• Caspase 3/7 Activity 20%
• Anti-glioblastoma 20%
• Migration Analysis 20%
• Independent Pathway 20%
• U87 Cell Line 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Glioblastoma 100%
• Decane 100%
• Cytotoxicity 80%
• Caspase 3 60%
• Neoplasm 40%
• Amino Acid 20%
• Reactive Oxygen Metabolite 20%
• Hydrogen Bond 20%
• IC50 20%
• Brain Cancer 20%
• Caspase 20%
• Phosphonate 20%
• Ether Derivative 20%
• Acetal 20%
• Cisplatin 20%
• Sulfonate 20%
• Sulfite 20%
• N Methyl Dextro Aspartic Acid Receptor 20%
• Sulfate 20%