Defined-size DNA triple crossover construct for molecular electronics: Modification, positioning and conductance properties

Veikko Linko, Jenni Leppiniemi, Seppo Tapio Paasonen, Vesa P. Hytönen, J. Jussi Toppari

Tutkimustuotos: ArtikkeliScientificvertaisarvioitu

15 Sitaatiot (Scopus)

Abstrakti

We present a novel, defined-size, small and rigid DNA template, a so-called B-A-B complex, based on DNA triple crossover motifs (TX tiles), which can be utilized in molecular scale patterning for nanoelectronics, plasmonics and sensing applications. The feasibility of the designed construct is demonstrated by functionalizing the TX tiles with one biotin-triethylene glycol (TEG) and efficiently decorating them with streptavidin, and furthermore by positioning and anchoring single thiol-modified B-A-B complexes to certain locations on a chip via dielectrophoretic trapping. Finally, we characterize the conductance properties of the non-functionalized construct, first by measuring DC conductivity and second by utilizing AC impedance spectroscopy in order to describe the conductivity mechanism of a single B-A-B complex using a detailed equivalent circuit model. This analysis also reveals further information about the conductivity of DNA structures in general.

AlkuperäiskieliEnglanti
Artikkeli275610
Sivut275610
JulkaisuNanotechnology
Vuosikerta22
Numero27
DOI - pysyväislinkit
TilaJulkaistu - 2011
OKM-julkaisutyyppiA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

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