Keyphrases
Design Evaluation
100%
Receptor-interacting Protein Kinase 1 (RIPK1)
100%
Synthetic Evaluation
100%
Active Methylene Compounds
100%
Arylhydrazone
100%
Tropomyosin Receptor Kinase B
100%
Anticancer Evaluation
100%
Glioblastoma
37%
NTRK1
25%
Adverse Effects
12%
In Vivo Analysis
12%
Molecular Dynamics Simulation
12%
Overexpression
12%
Dynamic Simulation
12%
Non-specific Binding
12%
Ligand Binding
12%
Hydrophobic Residues
12%
1,3-Diones
12%
IC50 Value
12%
Cytotoxicity
12%
In Cancer
12%
Oral Bioavailability
12%
Non-cancer
12%
Cancer Patients
12%
Novel Class
12%
Nitrophenyl
12%
Binding Potential
12%
RNA-seq Analysis
12%
Small Interfering RNA (siRNA)
12%
Structural Alterations
12%
Interaction Mode
12%
Brain Tumor
12%
Prognostic Biomarker
12%
Molecular Docking
12%
Cytotoxicity Activity
12%
Tumor Invasion
12%
Glioblastoma Therapy
12%
Tumor Migration
12%
Drug Likeness Properties
12%
TrkA
12%
Nerve Growth Factor
12%
MEF Cells
12%
Protein Targeting
12%
Lipinski's Rule of Five
12%
Ligand Stability
12%
Hydrazone Derivatives
12%
Oligoastrocytoma
12%
Hydrazineylidene
12%
Recurrent Glioblastoma
12%
U87 Glioma Cells
12%
Pharmacology, Toxicology and Pharmaceutical Science
Receptor
100%
Phosphotransferase
100%
Carbene
100%
Tropomyosin
88%
Chlornaphazine
88%
Glioblastoma
66%
Cytotoxicity
22%
Malignant Neoplasm
11%
Bioavailability
11%
IC50
11%
Binding Potential
11%
Astrocytoma
11%
Metastasis
11%
Tumor Marker
11%
Hydrazone Derivative
11%
Tumor Invasion
11%
Nerve Growth Factor
11%
Intracranial Tumor
11%
Lipinski's Rule of Five
11%
Biochemistry, Genetics and Molecular Biology
Anticancer
100%
Kinase
100%
Phosphotransferase
100%
Tropomyosin
88%
Cytotoxicity
22%
Protein Sequencing
11%
Docking (Molecular)
11%
Tumor Marker
11%
U87
11%
IC50
11%
Nerve Growth Factor
11%
Protein Targeting
11%
Computer Simulation
11%