Forward simulation and inverse dipole localization with the lowest order Raviart - Thomas elements for electroencephalography

S. Pursiainen, A. Sorrentino, C. Campi, M. Piana

    Tutkimustuotos: ArtikkeliScientificvertaisarvioitu

    27 Sitaatiot (Scopus)

    Abstrakti

    Electroencephalography is a non-invasive imaging modality in which a primary current density generated by the neural activity in the brain is to be reconstructed based on external electric potential measurements. This paper focuses on the finite element method (FEM) from both forward and inverse aspects. The goal is to establish a clear correspondence between the lowest order Raviart-Thomas basis functions and dipole sources as well as to show that the adopted FEM approach is computationally effective. Each basis function is associated with a dipole moment and a location. Four candidate locations are tested. Numerical experiments cover two different spherical multilayer head models, four mesh resolutions and two different forward simulation approaches, one based on FEM and another based on the boundary element method (BEM) with standard dipoles as sources. The forward simulation accuracy is examined through column- and matrix-wise relative errors as well as through performance in inverse dipole localization. A closed-form approximation of dipole potential was used as the reference forward simulation. The present approach is compared to the BEM and indirectly also to the recent FEM-based subtraction approach regarding both accuracy, computation time and accessibility of implementation.

    AlkuperäiskieliEnglanti
    Artikkeli045003
    JulkaisuInverse Problems
    Vuosikerta27
    Numero4
    DOI - pysyväislinkit
    TilaJulkaistu - huhtik. 2011
    OKM-julkaisutyyppiA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

    !!ASJC Scopus subject areas

    • Theoretical Computer Science
    • Signal Processing
    • Mathematical Physics
    • Computer Science Applications
    • Applied Mathematics

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