Genetic Factors in the Etiology of Preeclampsia/Eclampsia

Kenneth Ward, Hannele Laivuori, Robert N. Taylor

Tutkimustuotos: LukuScientificvertaisarvioitu

1 Sitaatiot (Scopus)

Abstrakti

Case reports describing familial clustering of eclampsia were first reported in the late 1800s, but Chesley was one of the first to perform a true genetic analysis. Chesley’s first edition text summarized his early investigations in hundreds of mother-daughter pairs. He reported that among daughters of women with eclampsia, 26% had preeclampsia in their first pregnancies. By contrast, the daughters-in-law control group had only an 8% rate of first-pregnancy preeclampsia. This comprehensively updated chapter will “fast-forward” the reader into the postgenomic era. As molecular analyses become less expensive and bioinformatic tools become more powerful, we are gaining new appreciation for the complexity of the etiologies, management strategies, and prevention of this syndrome.

AlkuperäiskieliEnglanti
OtsikkoChesley’s Hypertensive Disorders in Pregnancy
ToimittajatRobert N. Taylor, Kirk P. Conrad, Sandra T. Davidge, Anne Catherine Staff, James M. Roberts
KustantajaAcademic Press
Sivut45-69
Sivumäärä25
Painos5th
ISBN (elektroninen)9780128184172
ISBN (painettu)9780128184189
DOI - pysyväislinkit
TilaJulkaistu - 2022
OKM-julkaisutyyppiA3 Kirjan tai muun kokoomateoksen osa

Julkaisufoorumi-taso

  • Jufo-taso 2

!!ASJC Scopus subject areas

  • Medicine(all)

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