Maternal pre-pregnancy overweight and gestational diabetes and dietary intakes among young adult offspring

Nina Kaseva; Marja Vääräsmäki; Hanna Maria Matinolli; Marika Sipola; Marjaana Tikanmäki; Noora Kanerva; Kati Heinonen; Aulikki Lano; Dieter Wolke; Sture Andersson; Marjo Riitta Järvelin; Katri Räikkönen; Johan G. Eriksson; Satu Männistö; Eero Kajantie

doi:10.1038/s41387-020-00129-w

Maternal pre-pregnancy overweight and gestational diabetes and dietary intakes among young adult offspring

Nina Kaseva, Marja Vääräsmäki, Hanna Maria Matinolli, Marika Sipola, Marjaana Tikanmäki, Noora Kanerva, Kati Heinonen, Aulikki Lano, Dieter Wolke, Sture Andersson, Marjo Riitta Järvelin, Katri Räikkönen, Johan G. Eriksson, Satu Männistö, Eero Kajantie

Tutkimustuotos: Artikkeli › Scientific › vertaisarvioitu

2 Sitaatiot (Scopus)

Abstrakti

Background/Objectives: Maternal pre-pregnancy overweight/obesity and gestational diabetes (GDM) are associated with increased fat deposition in adult offspring. The purpose of this study was to identify if maternal pre-pregnancy overweight (body mass index (BMI) ≥ 25 kg/m²) or GDM are associated with dietary quality or intake in adult offspring. Subjects/Methods: Participants (n = 882) from two longitudinal cohort studies (ESTER Maternal Pregnancy Disorders Study and the Arvo Ylppö Longitudinal Study) completed a validated food-frequency questionnaire at a mean age of 24.2 years (SD 1.3). Diet quality was evaluated by a Recommended Finnish Diet Index (RDI). The study sample included offspring of normoglycaemic mothers with pre-pregnancy overweight/obesity (ONO = 155), offspring of mothers with GDM regardless of BMI (OGDM = 190) and offspring of mothers with normal weight and no GDM (controls; n = 537). Results: Among men, daily energy and macronutrient intakes were similar in ONO and controls. However, after adjusting for current offspring characteristics, including BMI, daily carbohydrate intake relative to total energy intake was higher in ONO-men [2.2 percentages of total energy intake (95% confidence interval 0.4, 4.0)]. In ONO-women, macronutrient intakes relative to total energy intake were similar with controls, while total daily energy intake seemed lower [−587.2 kJ/day (−1192.0, 4.4)]. After adjusting for confounders, this difference was attenuated. Adherence to a healthy diet, as measured by RDI, was similar in ONO and controls [mean difference: men 0.40 (−0.38, 1.18); women 0.25 (−0.50, 1.00)]. In OGDM vs. controls, total energy and macronutrient intakes were similar for both men and women. Also adherence to a healthy diet was similar [RDI: men 0.09 (−0.62, 0.80); women −0.17 (−0.93, 0.59)]. Conclusions: Our study suggested higher daily carbohydrate intake in male offspring exposed to maternal pre-pregnancy overweight/obesity, compared with controls. Prenatal exposure to GDM was not associated with adult offspring dietary intakes.

Alkuperäiskieli	Englanti
Artikkeli	26
Julkaisu	NUTRITION AND DIABETES
Vuosikerta	10
Numero	1
DOI - pysyväislinkit	https://doi.org/10.1038/s41387-020-00129-w
Tila	Julkaistu - 1 jouluk. 2020
Julkaistu ulkoisesti	Kyllä
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

!!ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism

YK:n kestävän kehityksen tavoitteet

Tämä tuotos edistää seuraavia kestävän kehityksen tavoitteita:

Pääsy asiakirjaan

10.1038/s41387-020-00129-w

Siteeraa tätä

Kaseva, N., Vääräsmäki, M., Matinolli, H. M., Sipola, M., Tikanmäki, M., Kanerva, N., Heinonen, K., Lano, A., Wolke, D., Andersson, S., Järvelin, M. R., Räikkönen, K., Eriksson, J. G., Männistö, S., & Kajantie, E. (2020). Maternal pre-pregnancy overweight and gestational diabetes and dietary intakes among young adult offspring. NUTRITION AND DIABETES, 10(1), [26]. https://doi.org/10.1038/s41387-020-00129-w

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title = "Maternal pre-pregnancy overweight and gestational diabetes and dietary intakes among young adult offspring",

abstract = "Background/Objectives: Maternal pre-pregnancy overweight/obesity and gestational diabetes (GDM) are associated with increased fat deposition in adult offspring. The purpose of this study was to identify if maternal pre-pregnancy overweight (body mass index (BMI) ≥ 25 kg/m2) or GDM are associated with dietary quality or intake in adult offspring. Subjects/Methods: Participants (n = 882) from two longitudinal cohort studies (ESTER Maternal Pregnancy Disorders Study and the Arvo Ylpp{\"o} Longitudinal Study) completed a validated food-frequency questionnaire at a mean age of 24.2 years (SD 1.3). Diet quality was evaluated by a Recommended Finnish Diet Index (RDI). The study sample included offspring of normoglycaemic mothers with pre-pregnancy overweight/obesity (ONO = 155), offspring of mothers with GDM regardless of BMI (OGDM = 190) and offspring of mothers with normal weight and no GDM (controls; n = 537). Results: Among men, daily energy and macronutrient intakes were similar in ONO and controls. However, after adjusting for current offspring characteristics, including BMI, daily carbohydrate intake relative to total energy intake was higher in ONO-men [2.2 percentages of total energy intake (95% confidence interval 0.4, 4.0)]. In ONO-women, macronutrient intakes relative to total energy intake were similar with controls, while total daily energy intake seemed lower [−587.2 kJ/day (−1192.0, 4.4)]. After adjusting for confounders, this difference was attenuated. Adherence to a healthy diet, as measured by RDI, was similar in ONO and controls [mean difference: men 0.40 (−0.38, 1.18); women 0.25 (−0.50, 1.00)]. In OGDM vs. controls, total energy and macronutrient intakes were similar for both men and women. Also adherence to a healthy diet was similar [RDI: men 0.09 (−0.62, 0.80); women −0.17 (−0.93, 0.59)]. Conclusions: Our study suggested higher daily carbohydrate intake in male offspring exposed to maternal pre-pregnancy overweight/obesity, compared with controls. Prenatal exposure to GDM was not associated with adult offspring dietary intakes.",

author = "Nina Kaseva and Marja V{\"a}{\"a}r{\"a}sm{\"a}ki and Matinolli, {Hanna Maria} and Marika Sipola and Marjaana Tikanm{\"a}ki and Noora Kanerva and Kati Heinonen and Aulikki Lano and Dieter Wolke and Sture Andersson and J{\"a}rvelin, {Marjo Riitta} and Katri R{\"a}ikk{\"o}nen and Eriksson, {Johan G.} and Satu M{\"a}nnist{\"o} and Eero Kajantie",

note = "Publisher Copyright: {\textcopyright} 2020, The Author(s).",

year = "2020",

month = dec,

day = "1",

doi = "10.1038/s41387-020-00129-w",

language = "English",

volume = "10",

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Kaseva, N, Vääräsmäki, M, Matinolli, HM, Sipola, M, Tikanmäki, M, Kanerva, N, Heinonen, K, Lano, A, Wolke, D, Andersson, S, Järvelin, MR, Räikkönen, K, Eriksson, JG, Männistö, S & Kajantie, E 2020, 'Maternal pre-pregnancy overweight and gestational diabetes and dietary intakes among young adult offspring', NUTRITION AND DIABETES, Vuosikerta 10, Nro 1, 26. https://doi.org/10.1038/s41387-020-00129-w

TY - JOUR

T1 - Maternal pre-pregnancy overweight and gestational diabetes and dietary intakes among young adult offspring

AU - Kaseva, Nina

AU - Vääräsmäki, Marja

AU - Matinolli, Hanna Maria

AU - Sipola, Marika

AU - Tikanmäki, Marjaana

AU - Kanerva, Noora

AU - Heinonen, Kati

AU - Lano, Aulikki

AU - Wolke, Dieter

AU - Andersson, Sture

AU - Järvelin, Marjo Riitta

AU - Räikkönen, Katri

AU - Eriksson, Johan G.

AU - Männistö, Satu

AU - Kajantie, Eero

PY - 2020/12/1

Y1 - 2020/12/1

N2 - Background/Objectives: Maternal pre-pregnancy overweight/obesity and gestational diabetes (GDM) are associated with increased fat deposition in adult offspring. The purpose of this study was to identify if maternal pre-pregnancy overweight (body mass index (BMI) ≥ 25 kg/m2) or GDM are associated with dietary quality or intake in adult offspring. Subjects/Methods: Participants (n = 882) from two longitudinal cohort studies (ESTER Maternal Pregnancy Disorders Study and the Arvo Ylppö Longitudinal Study) completed a validated food-frequency questionnaire at a mean age of 24.2 years (SD 1.3). Diet quality was evaluated by a Recommended Finnish Diet Index (RDI). The study sample included offspring of normoglycaemic mothers with pre-pregnancy overweight/obesity (ONO = 155), offspring of mothers with GDM regardless of BMI (OGDM = 190) and offspring of mothers with normal weight and no GDM (controls; n = 537). Results: Among men, daily energy and macronutrient intakes were similar in ONO and controls. However, after adjusting for current offspring characteristics, including BMI, daily carbohydrate intake relative to total energy intake was higher in ONO-men [2.2 percentages of total energy intake (95% confidence interval 0.4, 4.0)]. In ONO-women, macronutrient intakes relative to total energy intake were similar with controls, while total daily energy intake seemed lower [−587.2 kJ/day (−1192.0, 4.4)]. After adjusting for confounders, this difference was attenuated. Adherence to a healthy diet, as measured by RDI, was similar in ONO and controls [mean difference: men 0.40 (−0.38, 1.18); women 0.25 (−0.50, 1.00)]. In OGDM vs. controls, total energy and macronutrient intakes were similar for both men and women. Also adherence to a healthy diet was similar [RDI: men 0.09 (−0.62, 0.80); women −0.17 (−0.93, 0.59)]. Conclusions: Our study suggested higher daily carbohydrate intake in male offspring exposed to maternal pre-pregnancy overweight/obesity, compared with controls. Prenatal exposure to GDM was not associated with adult offspring dietary intakes.

AB - Background/Objectives: Maternal pre-pregnancy overweight/obesity and gestational diabetes (GDM) are associated with increased fat deposition in adult offspring. The purpose of this study was to identify if maternal pre-pregnancy overweight (body mass index (BMI) ≥ 25 kg/m2) or GDM are associated with dietary quality or intake in adult offspring. Subjects/Methods: Participants (n = 882) from two longitudinal cohort studies (ESTER Maternal Pregnancy Disorders Study and the Arvo Ylppö Longitudinal Study) completed a validated food-frequency questionnaire at a mean age of 24.2 years (SD 1.3). Diet quality was evaluated by a Recommended Finnish Diet Index (RDI). The study sample included offspring of normoglycaemic mothers with pre-pregnancy overweight/obesity (ONO = 155), offspring of mothers with GDM regardless of BMI (OGDM = 190) and offspring of mothers with normal weight and no GDM (controls; n = 537). Results: Among men, daily energy and macronutrient intakes were similar in ONO and controls. However, after adjusting for current offspring characteristics, including BMI, daily carbohydrate intake relative to total energy intake was higher in ONO-men [2.2 percentages of total energy intake (95% confidence interval 0.4, 4.0)]. In ONO-women, macronutrient intakes relative to total energy intake were similar with controls, while total daily energy intake seemed lower [−587.2 kJ/day (−1192.0, 4.4)]. After adjusting for confounders, this difference was attenuated. Adherence to a healthy diet, as measured by RDI, was similar in ONO and controls [mean difference: men 0.40 (−0.38, 1.18); women 0.25 (−0.50, 1.00)]. In OGDM vs. controls, total energy and macronutrient intakes were similar for both men and women. Also adherence to a healthy diet was similar [RDI: men 0.09 (−0.62, 0.80); women −0.17 (−0.93, 0.59)]. Conclusions: Our study suggested higher daily carbohydrate intake in male offspring exposed to maternal pre-pregnancy overweight/obesity, compared with controls. Prenatal exposure to GDM was not associated with adult offspring dietary intakes.

U2 - 10.1038/s41387-020-00129-w

DO - 10.1038/s41387-020-00129-w

M3 - Article

C2 - 32703940

AN - SCOPUS:85088362438

VL - 10

JO - NUTRITION AND DIABETES

JF - NUTRITION AND DIABETES

IS - 1

M1 - 26

ER -

Maternal pre-pregnancy overweight and gestational diabetes and dietary intakes among young adult offspring

Abstrakti

!!ASJC Scopus subject areas

YK:n kestävän kehityksen tavoitteet

Pääsy asiakirjaan

Sormenjälki

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