Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses

Leila N Varghese; Daniela Ungureanu; Nicholas P Liau; Young N Samuel; SN Young; Artem Laktyushin; Henrik Hammaren; Isabelle S Lucet; Nicos A Nicola; Olli Silvennoinen; Jeffrey J Babon; James M Murphy

doi:10.1042/bj20131516

Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses

Leila N Varghese, Daniela Ungureanu, Nicholas P Liau, Young N Samuel, SN Young, Artem Laktyushin, Henrik Hammaren, Isabelle S Lucet, Nicos A Nicola, Olli Silvennoinen, Jeffrey J Babon, James M Murphy

Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu

34 Sitaatiot (Scopus)

Alkuperäiskieli	Englanti
Sivut	395-405
Julkaisu	BIOCHEMICAL JOURNAL
Vuosikerta	458
Numero	2
DOI - pysyväislinkit	https://doi.org/10.1042/bj20131516
Tila	Julkaistu - 2014
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Julkaisufoorumi-taso

Jufo-taso 2

Pääsy asiakirjaan

10.1042/bj20131516

Siteeraa tätä

Varghese, L. N., Ungureanu, D., Liau, N. P., Samuel, Y. N., Young, SN., Laktyushin, A., Hammaren, H., Lucet, I. S., Nicola, N. A., Silvennoinen, O., Babon, J. J., & Murphy, J. M. (2014). Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses. BIOCHEMICAL JOURNAL, 458(2), 395-405. https://doi.org/10.1042/bj20131516

@article{e78ad7593e444fde81aad28bddef7248,

title = "Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses",

author = "Varghese, {Leila N} and Daniela Ungureanu and Liau, {Nicholas P} and Samuel, {Young N} and SN Young and Artem Laktyushin and Henrik Hammaren and Lucet, {Isabelle S} and Nicola, {Nicos A} and Olli Silvennoinen and Babon, {Jeffrey J} and Murphy, {James M}",

year = "2014",

doi = "10.1042/bj20131516",

language = "English",

volume = "458",

pages = "395--405",

journal = "BIOCHEMICAL JOURNAL",

issn = "0264-6021",

publisher = "Portland Press",

number = "2",

}

Varghese, LN, Ungureanu, D, Liau, NP, Samuel, YN, Young, SN, Laktyushin, A, Hammaren, H, Lucet, IS, Nicola, NA, Silvennoinen, O, Babon, JJ & Murphy, JM 2014, 'Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses', BIOCHEMICAL JOURNAL, Vuosikerta 458, Nro 2, Sivut 395-405. https://doi.org/10.1042/bj20131516

TY - JOUR

T1 - Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses

AU - Varghese, Leila N

AU - Ungureanu, Daniela

AU - Liau, Nicholas P

AU - Samuel, Young N

AU - Young, SN

AU - Laktyushin, Artem

AU - Hammaren, Henrik

AU - Lucet, Isabelle S

AU - Nicola, Nicos A

AU - Silvennoinen, Olli

AU - Babon, Jeffrey J

AU - Murphy, James M

PY - 2014

Y1 - 2014

U2 - 10.1042/bj20131516

DO - 10.1042/bj20131516

M3 - Article

SN - 0264-6021

VL - 458

SP - 395

EP - 405

JO - BIOCHEMICAL JOURNAL

JF - BIOCHEMICAL JOURNAL

IS - 2

ER -