Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

E. Porcu; S. Rüeger; K. Lepik; M. Agbessi; H. Ahsan; I. Alves; A. Andiappan; W. Arindrarto; P. Awadalla; A. Battle; F. Beutner; Jan M. Bonder; D. Boomsma; M. Christiansen; A. Claringbould; P. Deelen; T. Esko; M.-J. Favé; L. Franke; T. Frayling; S.A. Gharib; G. Gibson; B.T. Heijmans; G. Hemani; R. Jansen; M. Kähönen; A. Kalnapenkis; S. Kasela; J. Kettunen; Y. Kim; P. Kovacs; K. Krohn; J. Kronberg-Guzman; V. Kukushkina; B. Lee; T. Lehtimäki; M. Loeffler; U.M. Marigorta; H. Mei; L. Milani; G.W. Montgomery; M. Müller-Nurasyid; M. Nauck

doi:10.1038/s41467-019-10936-0

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

E. Porcu, S. Rüeger, K. Lepik, M. Agbessi, H. Ahsan, I. Alves, A. Andiappan, W. Arindrarto, P. Awadalla, A. Battle, F. Beutner, Jan M. Bonder, D. Boomsma, M. Christiansen, A. Claringbould, P. Deelen, T. Esko, M.-J. Favé, L. Franke, T. FraylingS.A. Gharib, G. Gibson, B.T. Heijmans, G. Hemani, R. Jansen, M. Kähönen, A. Kalnapenkis, S. Kasela, J. Kettunen, Y. Kim, P. Kovacs, K. Krohn, J. Kronberg-Guzman, V. Kukushkina, B. Lee, T. Lehtimäki, M. Loeffler, U.M. Marigorta, H. Mei, L. Milani, G.W. Montgomery, M. Müller-Nurasyid, M. Nauck

Kliinisen kemian yksikkö

Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu

172 Sitaatiot (Scopus)

Alkuperäiskieli	Englanti
Artikkeli	3300
Sivut	3300
Julkaisu	Nature Communications
Vuosikerta	10
Numero	1
DOI - pysyväislinkit	https://doi.org/10.1038/s41467-019-10936-0
Tila	Julkaistu - 2019
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Julkaisufoorumi-taso

Jufo-taso 3

Pääsy asiakirjaan

10.1038/s41467-019-10936-0

http://urn.fi/urn:nbn:fi:tuni-201910113822

Siteeraa tätä

Porcu, E., Rüeger, S., Lepik, K., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A., Arindrarto, W., Awadalla, P., Battle, A., Beutner, F., Bonder, J. M., Boomsma, D., Christiansen, M., Claringbould, A., Deelen, P., Esko, T., Favé, M.-J., Franke, L., ... Nauck, M. (2019). Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits. Nature Communications, 10(1), 3300. Artikkeli 3300. https://doi.org/10.1038/s41467-019-10936-0

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title = "Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits",

author = "E. Porcu and S. R{\"u}eger and K. Lepik and M. Agbessi and H. Ahsan and I. Alves and A. Andiappan and W. Arindrarto and P. Awadalla and A. Battle and F. Beutner and Bonder, {Jan M.} and D. Boomsma and M. Christiansen and A. Claringbould and P. Deelen and T. Esko and M.-J. Fav{\'e} and L. Franke and T. Frayling and S.A. Gharib and G. Gibson and B.T. Heijmans and G. Hemani and R. Jansen and M. K{\"a}h{\"o}nen and A. Kalnapenkis and S. Kasela and J. Kettunen and Y. Kim and P. Kovacs and K. Krohn and J. Kronberg-Guzman and V. Kukushkina and B. Lee and T. Lehtim{\"a}ki and M. Loeffler and U.M. Marigorta and H. Mei and L. Milani and G.W. Montgomery and M. M{\"u}ller-Nurasyid and M. Nauck",

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doi = "10.1038/s41467-019-10936-0",

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pages = "3300",

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Porcu, E, Rüeger, S, Lepik, K, Agbessi, M, Ahsan, H, Alves, I, Andiappan, A, Arindrarto, W, Awadalla, P, Battle, A, Beutner, F, Bonder, JM, Boomsma, D, Christiansen, M, Claringbould, A, Deelen, P, Esko, T, Favé, M-J, Franke, L, Frayling, T, Gharib, SA, Gibson, G, Heijmans, BT, Hemani, G, Jansen, R, Kähönen, M, Kalnapenkis, A, Kasela, S, Kettunen, J, Kim, Y, Kovacs, P, Krohn, K, Kronberg-Guzman, J, Kukushkina, V, Lee, B, Lehtimäki, T, Loeffler, M, Marigorta, UM, Mei, H, Milani, L, Montgomery, GW, Müller-Nurasyid, M & Nauck, M 2019, 'Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits', Nature Communications, Vuosikerta 10, Nro 1, 3300, Sivut 3300. https://doi.org/10.1038/s41467-019-10936-0

TY - JOUR

T1 - Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

AU - Porcu, E.

AU - Rüeger, S.

AU - Lepik, K.

AU - Agbessi, M.

AU - Ahsan, H.

AU - Alves, I.

AU - Andiappan, A.

AU - Arindrarto, W.

AU - Awadalla, P.

AU - Battle, A.

AU - Beutner, F.

AU - Bonder, Jan M.

AU - Boomsma, D.

AU - Christiansen, M.

AU - Claringbould, A.

AU - Deelen, P.

AU - Esko, T.

AU - Favé, M.-J.

AU - Franke, L.

AU - Frayling, T.

AU - Gharib, S.A.

AU - Gibson, G.

AU - Heijmans, B.T.

AU - Hemani, G.

AU - Jansen, R.

AU - Kähönen, M.

AU - Kalnapenkis, A.

AU - Kasela, S.

AU - Kettunen, J.

AU - Kim, Y.

AU - Kovacs, P.

AU - Krohn, K.

AU - Kronberg-Guzman, J.

AU - Kukushkina, V.

AU - Lee, B.

AU - Lehtimäki, T.

AU - Loeffler, M.

AU - Marigorta, U.M.

AU - Mei, H.

AU - Milani, L.

AU - Montgomery, G.W.

AU - Müller-Nurasyid, M.

AU - Nauck, M.

PY - 2019

Y1 - 2019

U2 - 10.1038/s41467-019-10936-0

DO - 10.1038/s41467-019-10936-0

M3 - Article

SN - 2041-1723

VL - 10

SP - 3300

JO - Nature Communications

JF - Nature Communications

IS - 1

M1 - 3300

ER -