Patterns of relapse following definitive treatment of head and neck squamous cell cancer by intensity modulated radiotherapy and weekly cisplatin

Venla Loimu; Juhani Collan; Leila Vaalavirta; Leif Bäck; Mika Kapanen; Antti Mäkitie; Mikko Tenhunen; Kauko Saarilahti

doi:10.1016/j.radonc.2010.10.015

Patterns of relapse following definitive treatment of head and neck squamous cell cancer by intensity modulated radiotherapy and weekly cisplatin

Venla Loimu
, Juhani Collan
, Leila Vaalavirta
, Leif Bäck
, Mika Kapanen
, Antti Mäkitie
, Mikko Tenhunen
, Kauko Saarilahti

Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu

25 Sitaatiot (Scopus)

Abstrakti

Eighty-three patients with oropharyngeal, hypopharyngeal or laryngeal cancer were treated with concomitant cisplatin 40 mg/m(2) once a week during the radiotherapy and IMRT up to a total dose of 70 Gy. The 2-year rate of local control, overall survival and disease specific survival were 84%, 82% and 89%, respectively. The corresponding 5-year Kaplan-Meier estimates were 79%, 69% and 76%.

Alkuperäiskieli	Englanti
Sivut	34-7
Sivumäärä	4
Julkaisu	Radiotherapy and Oncology
Vuosikerta	98
Numero	1
DOI - pysyväislinkit	https://doi.org/10.1016/j.radonc.2010.10.015
Tila	Julkaistu - tammik. 2011
Julkaistu ulkoisesti	Kyllä
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

YK:n kestävän kehityksen tavoitteet

Tämä tuotos edistää seuraavia kestävän kehityksen tavoitteita:

SDG 3 – Hyvä terveys ja hyvinvointi

Pääsy asiakirjaan

10.1016/j.radonc.2010.10.015

Siteeraa tätä

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title = "Patterns of relapse following definitive treatment of head and neck squamous cell cancer by intensity modulated radiotherapy and weekly cisplatin",

abstract = "Eighty-three patients with oropharyngeal, hypopharyngeal or laryngeal cancer were treated with concomitant cisplatin 40 mg/m(2) once a week during the radiotherapy and IMRT up to a total dose of 70 Gy. The 2-year rate of local control, overall survival and disease specific survival were 84\%, 82\% and 89\%, respectively. The corresponding 5-year Kaplan-Meier estimates were 79\%, 69\% and 76\%.",

keywords = "Adult, Aged, Antineoplastic Agents/administration \& dosage, Carcinoma/mortality, Carcinoma, Squamous Cell, Cisplatin/administration \& dosage, Combined Modality Therapy, Female, Head and Neck Neoplasms/mortality, Humans, Male, Middle Aged, Neoplasms, Squamous Cell/mortality, Radiotherapy, Intensity-Modulated/adverse effects, Squamous Cell Carcinoma of Head and Neck",

author = "Venla Loimu and Juhani Collan and Leila Vaalavirta and Leif B{\"a}ck and Mika Kapanen and Antti M{\"a}kitie and Mikko Tenhunen and Kauko Saarilahti",

year = "2011",

month = jan,

doi = "10.1016/j.radonc.2010.10.015",

language = "English",

volume = "98",

pages = "34--7",

journal = "Radiotherapy and Oncology",

issn = "0167-8140",

publisher = "Elsevier",

number = "1",

}

TY - JOUR

T1 - Patterns of relapse following definitive treatment of head and neck squamous cell cancer by intensity modulated radiotherapy and weekly cisplatin

AU - Loimu, Venla

AU - Collan, Juhani

AU - Vaalavirta, Leila

AU - Bäck, Leif

AU - Kapanen, Mika

AU - Mäkitie, Antti

AU - Tenhunen, Mikko

AU - Saarilahti, Kauko

PY - 2011/1

Y1 - 2011/1

N2 - Eighty-three patients with oropharyngeal, hypopharyngeal or laryngeal cancer were treated with concomitant cisplatin 40 mg/m(2) once a week during the radiotherapy and IMRT up to a total dose of 70 Gy. The 2-year rate of local control, overall survival and disease specific survival were 84%, 82% and 89%, respectively. The corresponding 5-year Kaplan-Meier estimates were 79%, 69% and 76%.

AB - Eighty-three patients with oropharyngeal, hypopharyngeal or laryngeal cancer were treated with concomitant cisplatin 40 mg/m(2) once a week during the radiotherapy and IMRT up to a total dose of 70 Gy. The 2-year rate of local control, overall survival and disease specific survival were 84%, 82% and 89%, respectively. The corresponding 5-year Kaplan-Meier estimates were 79%, 69% and 76%.

KW - Adult

KW - Aged

KW - Antineoplastic Agents/administration & dosage

KW - Carcinoma/mortality

KW - Carcinoma, Squamous Cell

KW - Cisplatin/administration & dosage

KW - Combined Modality Therapy

KW - Female

KW - Head and Neck Neoplasms/mortality

KW - Humans

KW - Male

KW - Middle Aged

KW - Neoplasms, Squamous Cell/mortality

KW - Radiotherapy, Intensity-Modulated/adverse effects

KW - Squamous Cell Carcinoma of Head and Neck

U2 - 10.1016/j.radonc.2010.10.015

DO - 10.1016/j.radonc.2010.10.015

M3 - Article

C2 - 21074875

SN - 0167-8140

VL - 98

SP - 34

EP - 37

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

IS - 1

ER -

Patterns of relapse following definitive treatment of head and neck squamous cell cancer by intensity modulated radiotherapy and weekly cisplatin

Abstrakti

YK:n kestävän kehityksen tavoitteet

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