Poststroke dementia is associated with recurrent ischaemic stroke

Gerli Sibolt; Sami Curtze; Susanna Melkas; Jukka Putaala; Tarja Pohjasvaara; Markku Kaste; Pekka J. Karhunen; Niku K J Oksala; Timo Erkinjuntti

doi:10.1136/jnnp-2012-304084

Poststroke dementia is associated with recurrent ischaemic stroke

Gerli Sibolt, Sami Curtze, Susanna Melkas, Jukka Putaala, Tarja Pohjasvaara, Markku Kaste, Pekka J. Karhunen, Niku K J Oksala, Timo Erkinjuntti

Tutkimustuotos: Artikkeli › Scientific › vertaisarvioitu

24 Sitaatiot (Scopus)

Abstrakti

Objective: To investigate whether poststroke dementia (PSD) diagnosed after ischaemic stroke predicts recurrent ischaemic stroke in long-term follow-up. Methods: We included 486 consecutive patients with ischaemic stroke (388 with first-ever stroke) admitted to Helsinki University Central Hospital who were followed-up for 12 years. Dementia was diagnosed in 115 patients using the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition (DSM-III) criteria. The effects of risk factors and PSD on survival free of recurrent stroke were estimated using Kaplan-Meier log-rank analyses, and the HRs for stroke recurrence were calculated using Cox proportional hazards models. Results: In the entire cohort, patients with PSD had a shorter mean time to recurrent stroke (7.13 years, 95% CI 6.20 to 8.06) than patients without dementia (9.41 years, 8.89 to 9.92: log rank p

Alkuperäiskieli	Englanti
Sivut	722-726
Sivumäärä	5
Julkaisu	JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Vuosikerta	84
Numero	7
DOI - pysyväislinkit	https://doi.org/10.1136/jnnp-2012-304084
Tila	Julkaistu - 2013
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Julkaisufoorumi-taso

Jufo-taso 2

Pääsy asiakirjaan

10.1136/jnnp-2012-304084

Siteeraa tätä

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title = "Poststroke dementia is associated with recurrent ischaemic stroke",

abstract = "Objective: To investigate whether poststroke dementia (PSD) diagnosed after ischaemic stroke predicts recurrent ischaemic stroke in long-term follow-up. Methods: We included 486 consecutive patients with ischaemic stroke (388 with first-ever stroke) admitted to Helsinki University Central Hospital who were followed-up for 12 years. Dementia was diagnosed in 115 patients using the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition (DSM-III) criteria. The effects of risk factors and PSD on survival free of recurrent stroke were estimated using Kaplan-Meier log-rank analyses, and the HRs for stroke recurrence were calculated using Cox proportional hazards models. Results: In the entire cohort, patients with PSD had a shorter mean time to recurrent stroke (7.13 years, 95% CI 6.20 to 8.06) than patients without dementia (9.41 years, 8.89 to 9.92: log rank p",

author = "Gerli Sibolt and Sami Curtze and Susanna Melkas and Jukka Putaala and Tarja Pohjasvaara and Markku Kaste and Karhunen, {Pekka J.} and Oksala, {Niku K J} and Timo Erkinjuntti",

year = "2013",

doi = "10.1136/jnnp-2012-304084",

language = "English",

volume = "84",

pages = "722--726",

journal = "JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY",

issn = "0022-3050",

publisher = "BMJ Publishing Group",

number = "7",

}

TY - JOUR

T1 - Poststroke dementia is associated with recurrent ischaemic stroke

AU - Sibolt, Gerli

AU - Curtze, Sami

AU - Melkas, Susanna

AU - Putaala, Jukka

AU - Pohjasvaara, Tarja

AU - Kaste, Markku

AU - Karhunen, Pekka J.

AU - Oksala, Niku K J

AU - Erkinjuntti, Timo

PY - 2013

Y1 - 2013

N2 - Objective: To investigate whether poststroke dementia (PSD) diagnosed after ischaemic stroke predicts recurrent ischaemic stroke in long-term follow-up. Methods: We included 486 consecutive patients with ischaemic stroke (388 with first-ever stroke) admitted to Helsinki University Central Hospital who were followed-up for 12 years. Dementia was diagnosed in 115 patients using the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition (DSM-III) criteria. The effects of risk factors and PSD on survival free of recurrent stroke were estimated using Kaplan-Meier log-rank analyses, and the HRs for stroke recurrence were calculated using Cox proportional hazards models. Results: In the entire cohort, patients with PSD had a shorter mean time to recurrent stroke (7.13 years, 95% CI 6.20 to 8.06) than patients without dementia (9.41 years, 8.89 to 9.92: log rank p

AB - Objective: To investigate whether poststroke dementia (PSD) diagnosed after ischaemic stroke predicts recurrent ischaemic stroke in long-term follow-up. Methods: We included 486 consecutive patients with ischaemic stroke (388 with first-ever stroke) admitted to Helsinki University Central Hospital who were followed-up for 12 years. Dementia was diagnosed in 115 patients using the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition (DSM-III) criteria. The effects of risk factors and PSD on survival free of recurrent stroke were estimated using Kaplan-Meier log-rank analyses, and the HRs for stroke recurrence were calculated using Cox proportional hazards models. Results: In the entire cohort, patients with PSD had a shorter mean time to recurrent stroke (7.13 years, 95% CI 6.20 to 8.06) than patients without dementia (9.41 years, 8.89 to 9.92: log rank p

U2 - 10.1136/jnnp-2012-304084

DO - 10.1136/jnnp-2012-304084

M3 - Article

AN - SCOPUS:84878746888

SN - 0022-3050

VL - 84

SP - 722

EP - 726

JO - JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

JF - JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

IS - 7

ER -

Poststroke dementia is associated with recurrent ischaemic stroke

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