Abstrakti
Controlled tablet disintegration is useful for chemical consistency checks. This study monitored the swelling of 54 analgesia tablets from two different batches, during 13-6-MHz brightness-mode sonication and simultaneous video recording. The tablets were placed on an acoustic reflector inside a container and sonicated from the top. Sonication shortened the displacement half-life by 17%-27%. During tablet swelling, their speed of sound increased linearly, confirming the linearity of this process. Diagnostic ultrasound significantly decreased tablet disintegration times, supporting the ultrasound-microbubble interaction hypothesis.
Alkuperäiskieli | Englanti |
---|---|
Artikkeli | SG1030 |
Julkaisu | Japanese Journal of Applied Physics |
Vuosikerta | 61 |
Numero | SG |
DOI - pysyväislinkit | |
Tila | Julkaistu - 2022 |
OKM-julkaisutyyppi | A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä |
Julkaisufoorumi-taso
- Jufo-taso 1