Robustness to sub-optimal temperatures of the processes of Tsr Cluster formation and positioning in Escherichia coli

Teppo Annila, Ramakanth Neeli-Venkata, Andre S. Ribeiro

    Tutkimustuotos: KonferenssiartikkeliScientificvertaisarvioitu

    Abstrakti

    Clustering and positioning of chemotaxis-associated proteins are believed to be essential steps for their proper functioning. We investigate the robustness of these processes to sub-optimal temperatures by studying the size and location of clusters of Tsr-Venus proteins in live cells. We find that the degree of clustering of Tsr proteins is maximal under optimal temperature. The data further suggests that the weakening of the clustering process in lower-than and higher-than optimal temperatures is not due to the same cause. Meanwhile, the location of the clusters is found to be weakly temperature independent, within the range tested. We conclude that while the clustering of Tsr is heavily temperature dependent, the localization is only weakly dependent, suggesting that the functionality of the proteins responsible for retaining Tsr-clusters at the cell poles, such as the Tol-Pal complex, is robust to suboptimal temperatures.

    AlkuperäiskieliEnglanti
    OtsikkoBIOINFORMATICS 2016 - 7th International Conference on Bioinformatics Models, Methods and Algorithms, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016
    KustantajaSCITEPRESS
    Sivut137-141
    Sivumäärä5
    ISBN (painettu)9789897581700
    TilaJulkaistu - 2016
    OKM-julkaisutyyppiA4 Artikkeli konferenssijulkaisussa
    TapahtumaINTERNATIONAL CONFERENCE ON BIOINFORMATICS MODELS, METHODS AND ALGORITHMS -
    Kesto: 1 tammik. 1900 → …

    Conference

    ConferenceINTERNATIONAL CONFERENCE ON BIOINFORMATICS MODELS, METHODS AND ALGORITHMS
    Ajanjakso1/01/00 → …

    Julkaisufoorumi-taso

    • Ei tasoa

    !!ASJC Scopus subject areas

    • Biomedical Engineering
    • Electrical and Electronic Engineering

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