Somatostatin-like immunoreactivity in human sympathetic ganglia

Riitta Järvi, Markku Pelto-Huikko, Pauli Helen, Antti Hervonen

Tutkimustuotos: ArtikkeliScientificvertaisarvioitu

17 Sitaatiot (Scopus)

Abstrakti

The localization of somatostatin-like immunore-activity (SOM-LI) was examined in human lumbar sympathetic ganglia using the peroxidase-antiperoxidase method. Few of the principal neurons showed immunolabelling for somatostatin and sparse networks of nerve terminals were unevenly associated with ganglion cells. Using light microscopy, the most intense SOM-LI was seen in the perinuclear zone of the neurons. Electron-microscopically, the staining was localized on the membranes of the Golgi apparatuses. In the nerve terminals, SOM-LI was seen inside the small vesicles (40-60 nm diameter). All neurons with SOM-LI were also found to be tyrosine-hydroxylase immunoreactive when excamined with a double-staining technique. These results provide evidence that somatostatin and noradrenaline co-exist in human sympathetic neurons.

AlkuperäiskieliEnglanti
Sivut1-5
Sivumäärä5
JulkaisuCELL AND TISSUE RESEARCH
Vuosikerta249
Numero1
DOI - pysyväislinkit
TilaJulkaistu - heinäk. 1987
Julkaistu ulkoisestiKyllä
OKM-julkaisutyyppiA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

!!ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Cell Biology

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