Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17

Keyphrases

• Stereochemical Hypothesis 100%
• UDP-glucuronosyltransferase (UGT) 2B7 100%
• UDP-glucuronosyltransferase 100%
• Diastereoselectivity 50%
• Conjugation 50%
• Spatial Arrangement 25%
• Inhibition Studies 25%
• Catalytic Site 25%
• Hydroxy Group 25%
• Catalytic Reaction 25%
• Corey-Bakshi-Shibata Reduction 25%
• Secondary Alcohols 25%
• Metabolic Enzymes 25%
• Pure Alcohol 25%
• R-enantiomer 25%
• Glucuronidation 25%
• Stereoisomers 25%
• Activity Quotient 25%
• Enantiomerically Pure 25%
• Stereoselectivity 25%

Chemistry

• UDP 100%
• Enantiomer 75%
• Diastereoselectivity 50%
• Metabolic 25%
• Hydroxyl Group 25%
• Secondary Alcohol 25%
• Stereoselectivity 25%
• Corey-Bakshi-Shibata Reduction 25%
• Stereoisomer 25%