TY - JOUR
T1 - Temperament, health-related behaviors, and autonomic cardiac regulation
T2 - The cardiovascular risk in young Finns study
AU - Puttonen, Sampsa
AU - Elovainio, Marko
AU - Kivimäki, Mika
AU - Koskinen, Tuomas
AU - Pulkki-Råback, Laura
AU - Viikari, Jorma S.A.
AU - Raitakari, Olli T.
AU - Keltikangas-Järvinen, Liisa
N1 - Funding Information:
This study was supported by the Academy of Finland (project numbers 209514, 209518, 77841, 210283, 123621 [L. P-R.]), the Finnish Foundation of Cardiovascular Research, the Emil Aaltonen Foundation, and the Research Funds of the University of Helsinki.
PY - 2008/5
Y1 - 2008/5
N2 - Temperament, as indicated by Cloninger's psychobiological model predicts coronary heart disease risk, but its association with autonomic cardiac regulation, a potential mediating mechanism, is unclear. We examined the associations between temperament traits and autonomic cardiac regulation in a resting situation in 798 women and 580 men derived from a population-based sample. After adjustment for age and sex, harm avoidance was associated with lower level of high-frequency (HF) variation, root mean square successive differences (RMSSDs), the percentage of successive R-R intervals >50 ms (pNN50) and higher heart rate (HR) (all p ≤ 0.005), suggesting that harm avoidance is related to low parasympathetic activity. Additional adjustments for behavioral factors attenuated these associations more than the adjustment for biological risk factors. Novelty seeking was associated with higher RMSSD (p = 0.007) and pNN50 (p = 0.012) and lower heart rate (p < 0.001). With adjustment for behavioral risk factors, the associations with RMSSD (p = 0.136) and pNN50 (p = 0.236) attenuated to the null, but adjustment for biological risk factors had little effect. Reward dependence and persistence were unrelated to indices of cardiac regulation.
AB - Temperament, as indicated by Cloninger's psychobiological model predicts coronary heart disease risk, but its association with autonomic cardiac regulation, a potential mediating mechanism, is unclear. We examined the associations between temperament traits and autonomic cardiac regulation in a resting situation in 798 women and 580 men derived from a population-based sample. After adjustment for age and sex, harm avoidance was associated with lower level of high-frequency (HF) variation, root mean square successive differences (RMSSDs), the percentage of successive R-R intervals >50 ms (pNN50) and higher heart rate (HR) (all p ≤ 0.005), suggesting that harm avoidance is related to low parasympathetic activity. Additional adjustments for behavioral factors attenuated these associations more than the adjustment for biological risk factors. Novelty seeking was associated with higher RMSSD (p = 0.007) and pNN50 (p = 0.012) and lower heart rate (p < 0.001). With adjustment for behavioral risk factors, the associations with RMSSD (p = 0.136) and pNN50 (p = 0.236) attenuated to the null, but adjustment for biological risk factors had little effect. Reward dependence and persistence were unrelated to indices of cardiac regulation.
KW - Blood pressure
KW - Cardiac control
KW - Cholesterol
KW - Health behaviors
KW - Heart rate variability
KW - Personality
KW - Temperament
KW - Temperament and character inventory
U2 - 10.1016/j.biopsycho.2008.03.003
DO - 10.1016/j.biopsycho.2008.03.003
M3 - Article
C2 - 18417269
AN - SCOPUS:43049101039
SN - 0301-0511
VL - 78
SP - 204
EP - 210
JO - BIOLOGICAL PSYCHOLOGY
JF - BIOLOGICAL PSYCHOLOGY
IS - 2
ER -